K
Ken Donaldson
Researcher at University of Edinburgh
Publications - 392
Citations - 50261
Ken Donaldson is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Inflammation & Bronchoalveolar lavage. The author has an hindex of 109, co-authored 385 publications receiving 47072 citations. Previous affiliations of Ken Donaldson include Edinburgh Napier University & Royal College of Surgeons of Edinburgh.
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Journal ArticleDOI
Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study.
Craig A Poland,Rodger Duffin,Ian A. Kinloch,Andrew D. Maynard,William A Wallace,Anthony Seaton,Vicki Stone,Simon Brown,William MacNee,Ken Donaldson +9 more
TL;DR: Exposing the mesothelial lining of the body cavity of mice to long multiwalled carbon nanotubes results in asbestos-like, length-dependent, pathogenic behaviour, including inflammation and the formation of lesions known as granulomas.
Journal ArticleDOI
Particulate air pollution and acute health effects
TL;DR: It is suggested that ultra-fine particles in the nature of the urban particulate cloud are able to provoke alveolar inflammation, with release of mediators capable, in susceptible individuals, of causing exacerbations of lung disease and of increasing blood coagulability, thus also explaining the observed increases in cardiovascular deaths associated with urban pollution episodes.
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Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy.
Günter Oberdörster,Andrew D. Maynard,Ken Donaldson,Vincent Castranova,Julie W. Fitzpatrick,Kevin D. Ausman,Janet M. Carter,Barbara Karn,Barbara Karn,Wolfgang G. Kreyling,David Y. Lai,Stephen S. Olin,Nancy A. Monteiro-Riviere,David B. Warheit,Hong Yang +14 more
TL;DR: The working group report presents a broad data gathering strategy applicable to this early stage in the development of a risk assessment process for nanomaterials, and there is a strong likelihood that biological activity of nanoparticles will depend on physicochemical parameters not routinely considered in toxicity screening studies.
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Safe handling of nanotechnology
Andrew D. Maynard,Robert Aitken,Tilman Butz,Vicki L. Colvin,Ken Donaldson,Günter Oberdörster,Martin A. Philbert,John Ryan,Anthony Seaton,Vicki Stone,Sally S. Tinkle,Lang Tran,Nigel J. Walker,David B. Warheit +13 more
TL;DR: The pursuit of responsible nanotechnologies can be tackled through a series of grand challenges, argue Andrew D. Maynard and his co-authors, and if they and their colleagues can rise to these challenges the true extent of any risks involved should become clear.
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The potential risks of nanomaterials: a review carried out for ECETOC
Paul J. A. Borm,David Robbins,Stephan Haubold,Thomas A. J. Kuhlbusch,Heinz Fissan,Ken Donaldson,Roel P. F. Schins,Vicki Stone,Wolfgang G. Kreyling,Jürgen Lademann,Jean Krutmann,David B. Warheit,Eva Oberdörster +12 more
TL;DR: This review shows that only few specific nanoparticles have been investigated in a limited number of test systems and extrapolation of this data to other materials is not possible, and limited ecotoxicological data for nanomaterials precludes a systematic assessment of the impact of Nanoparticles on ecosystems.