Kristian Gundersen

TL;DR: The existence of the 2X-MHC isoform was confirmed by immunoblotting analysis using muscles containing 2X fibres as a major component, such as the normal and hyperthyroid diaphragm, and the soleus muscle after high frequency chronic stimulation.

TL;DR: It is shown that crucian carp living in normoxic water have gills that lack protruding lamellae, the primary site of O2 uptake in fish, the first demonstration of an adaptive and reversible gross morphological change in the respiratory organ of an adult vertebrate in response to changes in the availability of oxygen.

TL;DR: In vivo imaging techniques are used to study live myon nuclei belonging to distinct muscle fibers and observe that new myonuclei are added before any major increase in size during overload, and the old and newly acquired nuclei are retained during severe atrophy caused by subsequent denervation lasting for a considerable period of the animal’s lifespan.

TL;DR: The non‐random and often row‐like distribution of nuclei observed in muscle fibres may reflect regulatory mechanisms whereby nuclei repel each other in order to minimize transport distances.

TL;DR: The expression of 4 myosin heavy chain (MHC) isoforms was analyzed in the rat soleus (SOL) and extensor digitorum longus (EDL) muscles after denervation and chronic electric stimulation and coexistence of different MHC types in the same fiber was frequently observed in stimulated muscles.