L
L. Bruce Gladden
Researcher at University of Michigan
Publications - 85
Citations - 3158
L. Bruce Gladden is an academic researcher from University of Michigan. The author has contributed to research in topics: Skeletal muscle & Muscle contraction. The author has an hindex of 26, co-authored 78 publications receiving 2620 citations. Previous affiliations of L. Bruce Gladden include Auburn University.
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Journal ArticleDOI
Blood Lactate Measurements and Analysis during Exercise: A Guide for Clinicians
TL;DR: Blood lactate concentration ([La−]b) is one of the most often measured parameters during clinical exercise testing as well as during performance testing of athletes and is useful in prescribing exercise intensities for most diseased and nondiseased patients alike.
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Faster adjustment of O2delivery does not affect V˙o 2 on-kinetics in isolated in situ canine muscle
TL;DR: In the present experimental model, elimination of any delay in O2 delivery during the rest-to-contraction transition did not affect muscle V(O2) kinetics, which suggests that this kinetics was mainly set by an intrinsic inertia of oxidative metabolism.
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Lactate is always the end product of glycolysis
TL;DR: The proposition, analogous to the phosphocreatine shuttle, purports that pyruvate, NAD+, NADH, and La− are held uniformly near equilibrium throughout the cell cytosol due to the high activity of LDH.
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Lactate Metabolism: Historical Context, Prior Misinterpretations, And Current Understanding
Brian S. Ferguson,Matthew J. Rogatzki,Matthew L. Goodwin,Matthew L. Goodwin,Daniel A. Kane,Zachary B Rightmire,L. Bruce Gladden +6 more
TL;DR: Current understanding of La− metabolism is synthesized via an appraisal of its robust experimental history, particularly in exercise physiology, to highlight La−’s central role in metabolism and amplifies the understanding of past research.
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Peripheral O2 diffusion does not affect V˙o 2 on-kinetics in isolated in situ canine muscle
TL;DR: Electrolysis of canine gastrocnemius muscles during transitions from rest to 3 min of electrically stimulated isometric tetanic contractions did not affect muscle V(O2) on- kinetics, and enhancement of peripheral O2 diffusion during the rest-to-contraction transition did not affected muscle O2 on-kinetics.