L
Laura Villa
Researcher at Istituto Superiore di Sanità
Publications - 107
Citations - 11086
Laura Villa is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Plasmid & Salmonella enterica. The author has an hindex of 41, co-authored 97 publications receiving 9057 citations. Previous affiliations of Laura Villa include Sapienza University of Rome.
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Journal ArticleDOI
In Silico Detection and Typing of Plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing
Alessandra Carattoli,Ea Zankari,Aurora García-Fernández,Mette Voldby Larsen,Ole Lund,Laura Villa,Frank Møller Aarestrup,Henrik Hasman +7 more
TL;DR: Two easy-to-use Web tools for in silico detection and characterization of whole-genome sequence (WGS) and whole-plasmid sequence data from members of the family Enterobacteriaceae are designed and developed.
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Identification of plasmids by PCR-based replicon typing
Alessandra Carattoli,Alessia Bertini,Laura Villa,Vincenzo Falbo,Katie L. Hopkins,E. John Threlfall +5 more
TL;DR: Results indicated that the inc/rep PCR method demonstrates high specificity and sensitivity in detecting replicons on reference plasmids and also revealed the presence of recurrent and common plasmid in epidemiologically unrelated Salmonella isolates of different serotypes.
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Replicon sequence typing of IncF plasmids carrying virulence and resistance determinants
TL;DR: The ability to recognize and sub-categorize IncF plasmids by RST in homogeneous groups on the basis of their phylogenetic relatedness can be helpful in analysing their distribution in nature and discovering their evolutionary origin.
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Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.
Alessandra Carattoli,Laura Villa,Claudia Feudi,Claudia Feudi,Ludovica Curcio,Serenella Orsini,Andrea Luppi,Giovanni Pezzotti,Chiara Francesca Magistrali +8 more
TL;DR: Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe.
Journal ArticleDOI
Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes.
Ana Rita Rebelo,Valeria Bortolaia,Jette Kjeldgaard,Susanne Karlsmose Pedersen,Pimlapas Leekitcharoenphon,Inge M Hansen,Beatriz Guerra,Burkhard Malorny,Maria Borowiak,Jens A. Hammerl,Antonio Battisti,Alessia Franco,Patricia Alba,Agnès Perrin-Guyomard,Sophie A. Granier,Cristina De Frutos Escobar,Surbhi Malhotra-Kumar,Laura Villa,Alessandra Carattoli,Rene S. Hendriksen +19 more
TL;DR: The multiplex PCR protocol should be particularly interesting in settings or laboratories with limited resources for performing genetic analysis as it provides information on the mechanism of colistin resistance without requiring genome sequencing.