L
Lothar Schermelleh
Researcher at University of Oxford
Publications - 97
Citations - 11021
Lothar Schermelleh is an academic researcher from University of Oxford. The author has contributed to research in topics: Chromatin & Cohesin. The author has an hindex of 46, co-authored 90 publications receiving 9498 citations. Previous affiliations of Lothar Schermelleh include École Polytechnique Fédérale de Lausanne & Protein Sciences.
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Journal ArticleDOI
A guide to super-resolution fluorescence microscopy
TL;DR: These new super-resolution technologies are either based on tailored illumination, nonlinear fluorophore responses, or the precise localization of single molecules and have created unprecedented new possibilities to investigate the structure and function of cells.
Journal ArticleDOI
Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy
Lothar Schermelleh,Peter M. Carlton,Sebastian Haase,Lin Shao,Lukman Winoto,Peter Kner,Brian Burke,M. Cristina Cardoso,David A. Agard,Mats G. L. Gustafsson,Heinrich Leonhardt,John W. Sedat +11 more
TL;DR: Three-dimensional structured illumination microscopy (3D-SIM) opens new and facile possibilities to analyze subcellular structures beyond the diffraction limit of the emitted light.
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Super-resolution microscopy demystified
Lothar Schermelleh,Alexia Ferrand,Thomas R Huser,Christian Eggeling,Markus Sauer,Oliver Biehlmaier,Drummen Gpc. +6 more
TL;DR: An overview of current super-resolution microscopy techniques is given and guidance on how best to use them to foster biological discovery is provided.
Journal ArticleDOI
Targeting and tracing antigens in live cells with fluorescent nanobodies
Ulrich Rothbauer,Kourosh Zolghadr,Sergey Tillib,Danny Nowak,Lothar Schermelleh,Anja Gahl,Natalija Backmann,Katja Conrath,Serge Muyldermans,M Christina Cardoso,Heinrich Leonhardt +10 more
TL;DR: It is demonstrated that chromobodies can recognize and trace antigens in different subcellular compartments throughout S phase and mitosis.
Journal ArticleDOI
Cortical Constriction During Abscission Involves Helices of ESCRT-III–Dependent Filaments
Julien Guizetti,Julien Guizetti,Lothar Schermelleh,Jana Mäntler,Sandra Maar,Ina Poser,Heinrich Leonhardt,Thomas Müller-Reichert,Daniel W. Gerlich,Daniel W. Gerlich +9 more
TL;DR: In this article, the endosomal sorting complex required for transport (ESCRT)-III co-localized with constriction zones and was required for assembly of 17-nanometer-diameter filaments, which narrowed the cortex of the intercellular bridge to a single stalk.