L
Luanne M. Metz
Researcher at University of Calgary
Publications - 169
Citations - 14327
Luanne M. Metz is an academic researcher from University of Calgary. The author has contributed to research in topics: Multiple sclerosis & Depression (differential diagnoses). The author has an hindex of 49, co-authored 159 publications receiving 13386 citations. Previous affiliations of Luanne M. Metz include Foothills Medical Centre.
Papers
More filters
Journal ArticleDOI
Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria".
Chris H. Polman,Stephen C. Reingold,Gilles Edan,Massimo Filippi,Hans-Peter Hartung,Ludwig Kappos,Fred D. Lublin,Luanne M. Metz,Henry F. McFarland,Paul O'Connor,Magnhild Sandberg-Wollheim,Alan J. Thompson,Brian G. Weinshenker,Jerry S. Wolinsky +13 more
TL;DR: New evidence and consensus now strengthen the role of these criteria in the multiple sclerosis diagnostic workup to demonstrate dissemination of lesions in time, to clarify the use of spinal cord lesions, and to simplify diagnosis of primary progressive disease.
Journal ArticleDOI
A full genome search in multiple sclerosis
George C. Ebers,K Kukay,Dennis E. Bulman,A D Sadovnick,George P.A. Rice,Carol M. Anderson,H. Armstrong,K Cousin,Robert B. Bell,W Hader,Donald W. Paty,S Hashimoto,Joel Oger,Pierre Duquette,Sharon Warren,T. Gray,Paul O'Connor,Avindra Nath,A. Auty,Luanne M. Metz,Gordon S. Francis,J E Paulseth,T J Murray,William Pryse-Phillips,R. F. Nelson,Matthew L. Freedman,Donald G. Brunet,Jean-Pierre Bouchard,David A. Hinds,Neil Risch +29 more
TL;DR: The results support genetic epidemiological evidence that several genes interact epistatically to determine heritable susceptibility in multiple sclerosis.
Journal ArticleDOI
The promise of minocycline in neurology
TL;DR: The evidence for the efficacy of minocyCline in several animal models of neurological disease is described, the mechanisms by which minocycline affects a range of neurological diseases with diverse causes are discussed, and the emerging investigation of minocrycline in clinical neurology is introduced.
Journal ArticleDOI
Major depression in multiple sclerosis A population-based perspective
TL;DR: The prevalence of major depression in the population with MS is elevated and exceeds that associated with having one or more other long-term conditions.
Journal ArticleDOI
Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis.
TL;DR: Results indicate that minocycline may constitute a safe and inexpensive therapy for multiple sclerosis and inhibit MMP activity, reduced production of MMP-9 and decreased the transmigration of T lymphocytes across a fibronectin matrix barrier.