L
Luigi Brunetti
Researcher at Rutgers University
Publications - 96
Citations - 2070
Luigi Brunetti is an academic researcher from Rutgers University. The author has contributed to research in topics: Odds ratio & Phytochemical. The author has an hindex of 19, co-authored 96 publications receiving 1440 citations. Previous affiliations of Luigi Brunetti include Robert Wood Johnson University Hospital & Somerset Medical Center.
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Journal ArticleDOI
An Update on Current Therapeutic Drugs Treating COVID-19.
Renyi Wu,Lujing Wang,Hsiao-Chen Dina Kuo,Ahmad Shannar,Rebecca Peter,Pochung Jordan Chou,Shanyi Li,Rasika Hudlikar,Xia Liu,Xia Liu,Zhigang Liu,George J. Poiani,George J. Poiani,Louis F. Amorosa,Luigi Brunetti,Luigi Brunetti,Ah-Ng Tony Kong +16 more
TL;DR: It is hoped that this review will provide useful and most updated therapeutic drugs to prevent, control, and treat COVID-19 patients until the approval of vaccines and specific drugs targeting SARS-CoV-2.
Journal ArticleDOI
Colchicine in COVID-19: an Old Drug, New Use.
TL;DR: It is discussed how colchicine interferes with several inflammatory pathways, including inhibition of neutrophil chemotaxis, adhesion, and mobilization; disruption of superoxide production, inflammasome inhibition, and tumor necrosis factor reduction; and its possible antiviral properties.
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Chemical profiling and pharmaco-toxicological activity of Origanum sipyleum extracts: Exploring for novel sources for potential therapeutic agents
Gokhan Zengin,Claudio Ferrante,Giustino Orlando,Dimitrina Zheleva-Dimitrova,Reneta Gevrenova,Lucia Recinella,Annalisa Chiavaroli,Sheila Leone,Luigi Brunetti,Muhammad Zakariyyah Aumeeruddy,Abdurrahman Aktumsek,Mohamad Fawzi Mahomoodally,Paola Angelini,Stefano Covino,Roberto Venanzoni,Bruno Tirillini,Luigi Menghini +16 more
TL;DR: The results are intriguing and suggest potential applications O. sipyleum extracts as sources of natural agents for the management of clinical symptoms related to ulcerative colitis, characterized by increased burden of oxidative stress and microbiome dysbiosis.
Journal ArticleDOI
Multiple pharmacognostic characterization on hemp commercial cultivars: Focus on inflorescence water extract activity
Claudio Ferrante,Lucia Recinella,Maurizio Ronci,Luigi Menghini,Luigi Brunetti,Annalisa Chiavaroli,Sheila Leone,Luigi Di Iorio,Simone Carradori,Bruno Tirillini,Paola Angelini,Stefano Covino,Roberto Venanzoni,Giustino Orlando +13 more
TL;DR: The potential efficacy of hemp inflorescence water extracts in managing the clinical symptoms related to ulcerative colitis is supported and the phytochemical profile displays a better antioxidant and anti-inflammatory profile.
Journal ArticleDOI
Risk Factors and Outcomes of Hospitalized Patients With Severe Coronavirus Disease 2019 (COVID-19) and Secondary Bloodstream Infections: A Multicenter Case-Control Study.
Pinki J. Bhatt,Stephanie Shiau,Luigi Brunetti,Yingda Xie,Kinjal Solanki,Shaza Khalid,Sana Mohayya,Pak Ho Au,Christopher Pham,Priyanka Uprety,Ronald Nahass,Navaneeth Narayanan +11 more
TL;DR: Hospitalized adult patients with severe COVID-19 and sBSI had a more severe initial presentation, prolonged hospital course, and worse clinical outcomes, and to maintain antimicrobial stewardship principles, further prospective studies are necessary to better characterize risk factors and prediction modeling.