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Renyi Wu

Researcher at Rutgers University

Publications -  47
Citations -  1759

Renyi Wu is an academic researcher from Rutgers University. The author has contributed to research in topics: Epigenetics & DNA methylation. The author has an hindex of 19, co-authored 45 publications receiving 1167 citations. Previous affiliations of Renyi Wu include Chinese Academy of Sciences.

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An Update on Current Therapeutic Drugs Treating COVID-19.

TL;DR: It is hoped that this review will provide useful and most updated therapeutic drugs to prevent, control, and treat COVID-19 patients until the approval of vaccines and specific drugs targeting SARS-CoV-2.
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DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice.

TL;DR: Epigenomic changes in DNA CpG methylation in the inflammatory response from colitis-associated colon cancer and the reversal of their Cpg methylation changes by curcumin are shown for the first time.
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Dietary Phytochemicals and Cancer Chemoprevention: A Perspective on Oxidative Stress, Inflammation, and Epigenetics.

TL;DR: The beneficial effects of dietary phytochemicals on cancer development warrant further investigation to provide additional impetus for clinical translational studies.
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Phenethyl isothiocyanate (PEITC) suppresses prostate cancer cell invasion epigenetically through regulating microRNA-194.

TL;DR: The results indicate that miR-194 downregulates the expression of oncogenic MMP2 and MMP9 by targeting BMP1, which suggests a potential new mechanistic target by which PEITC suppresses prostate cancer cell invasiveness.
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The dietary flavone luteolin epigenetically activates the Nrf2 pathway and blocks cell transformation in human colorectal cancer HCT116 cells.

TL;DR: The findings suggest that LUT may exert its antitumor activity in part via epigenetic modifications of the Nrf2 gene with subsequent induction of its downstream antioxidative stress pathway.