M
Marcel P. Bruchez
Researcher at Carnegie Mellon University
Publications - 167
Citations - 25329
Marcel P. Bruchez is an academic researcher from Carnegie Mellon University. The author has contributed to research in topics: Quantum dot & Endocytosis. The author has an hindex of 44, co-authored 158 publications receiving 24166 citations. Previous affiliations of Marcel P. Bruchez include University of California, Berkeley & University of Pittsburgh.
Papers
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
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Organization of 'nanocrystal molecules' using DNA
A. Paul Alivisatos,A. Paul Alivisatos,Kai Johnsson,Xiaogang Peng,Xiaogang Peng,Troy E. Wilson,Colin J. Loweth,Marcel P. Bruchez,Marcel P. Bruchez,Peter G. Schultz +9 more
TL;DR: A strategy for the synthesis of 'nanocrystal molecules', in which discrete numbers of gold nanocrystals are organized into spatially defined structures based on Watson-Crick base-pairing interactions is described.
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Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots
Xingyong Wu,Hongjian Liu,Jianquan Liu,Kari Haley,Joseph A. Treadway,J. Peter Larson,Nianfeng Ge,Frank Peale,Marcel P. Bruchez +8 more
TL;DR: Using QDs linked to immunoglobulin G and streptavidin to label the breast cancer marker Her2, to stain actin and microtubule fibers in the cytoplasm, and to detect nuclear antigens inside the nucleus indicate that QD-based probes can be very effective in cellular imaging and offer substantial advantages over organic dyes in multiplex target detection.
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Water-Soluble Quantum Dots for Multiphoton Fluorescence Imaging in Vivo
Daniel R. Larson,Warren R. Zipfel,Rebecca M. Williams,S. W. Clark,Marcel P. Bruchez,Frank W. Wise,Watt W. Webb +6 more
TL;DR: This work characterized water-soluble cadmium selenide–zinc sulfide quantum dots for multiphoton imaging in live animals and found no evidence of blinking (fluorescence intermittency) in solution on nanosecond to millisecond time scales.
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Noninvasive Imaging of Quantum Dots in Mice
TL;DR: Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.