Marcus W. Agelink

TL;DR: There was a significantly negative correlation between the HAM-D scores and the vagal HRV indices, suggesting a direct association between the severity of depressive symptoms and the modulation of cardiovagal activity in patients with major depression.

TL;DR: The authors computed age- and gender-dependent normal values for each of the HRV indices studied here and discuss the clinical consequences arising from gender differences in HRV.

TL;DR: Serial standardized recordings of conventional electrocardiograms and computer-calculated measurements of 5-minute resting heart rate variability (HRV) were obtained from 51 medication-free inpatients with schizophrenia and the most important findings were the following: clozapine, olanzapines, and sertindole all prolonged mean frequency-corrected QTc times, which, in the case of sERTindole, proved to be significant.

TL;DR: The data suggest that pathways presumably involved in mood regulation have structural pathology in affective disorders with more pronounced abnormalities in bipolar disorder.

TL;DR: Patients with MD may suffer from functional disturbances in the interaction between the sympathetic and parasympathetic autonomic tree, and the pattern of autonomic changes during treatment suggests that nefazodone induced a dose dependent, serotonergically-mediated down-regulation of the sympathetic tone.