Journal ArticleDOI
Standardized tests of heart rate variability: normal ranges obtained from 309 healthy humans, and effects of age, gender, and heart rate.
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TLDR
The authors computed age- and gender-dependent normal values for each of the HRV indices studied here and discuss the clinical consequences arising from gender differences in HRV.Abstract:
The authors undertook this study to determine the effects of age, gender, and heart rate (HR) on the results of cardiac autonomic function tests for measuring heart rate variability (HRV) in a large sample of healthy subjects (n = 309). Conventional tests (deep breathing, maximum/minimum 30:15 ratio), and a standardized 5-minute resting study, including spectral analysis of HR, were used. The main findings included (1) the indices of all tests, except for the ratio of the low- (LF) to high-frequency (HF) spectral power (LF/HF ratio) and HR itself, are inversely related to age in both sexes; (2) the 5-minute spectral bands (except for the LF/HF ratio), the variation coefficient, expiratory-inspiratory ratio during deep breathing, and the maximum/minimum 30:15 ratio are independent of HR; (3) women up to the age of 55 years have a higher resting HR compared with men; (4) young and middle-aged women show a significantly lower LF power and LF/HF ratio compared with age-matched men, whereas no significant gender differences are observed in the absolute HF power. The authors computed age- and gender-dependent normal values for each of the HRV indices studied here and discuss the clinical consequences arising from gender differences in HRV.read more
Citations
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Journal ArticleDOI
Sex differences in healthy human heart rate variability: A meta-analysis.
TL;DR: Although women showed greater mean heart rate, they showed greater vagal activity indexed by HF power of HRV, and underlying mechanisms of these findings are discussed.
Journal ArticleDOI
Revisions to the Canadian Emergency Department Triage and Acuity Scale (CTAS) adult guidelines.
Michael J. Bullard,Erin Musgrave,David Warren,Bernard Unger,Thora Skeldon,Rob Grierson,Etienne van der Linde,Janel Swain +7 more
TL;DR: The Canadian Emergency Department Triage and Acuity Scale (CTAS) has been widely adopted in emergency departments across Canada and abroad since its initial publication in 1999 and studies looking at reliability and validity of CTAS using computerized decision support systems have been generally generally positive.
Journal ArticleDOI
Relationship between major depression and heart rate variability. Clinical consequences and implications for antidepressive treatment.
TL;DR: There was a significantly negative correlation between the HAM-D scores and the vagal HRV indices, suggesting a direct association between the severity of depressive symptoms and the modulation of cardiovagal activity in patients with major depression.
Journal ArticleDOI
Short-term heart rate variability--influence of gender and age in healthy subjects.
TL;DR: Gender and age influences need to be considered when performing HRV studies even if these influences only partly differ, as significant modifications of the indices according to gender could be obtained in nearly all of the domains.
Journal ArticleDOI
Dose-response relationship of the cardiovascular adaptation to endurance training in healthy adults: how much training for what benefit?
TL;DR: Increases in R-wave-R-wave interval and cardiovascular variability indexes are consistent with an augmentation of vagal modulation of HR after exercise training, and appear to achieve this response as well as a modest hypotensive effect from decreasing vascular resistance.
References
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Journal ArticleDOI
Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology.
Alan John Camm,Marek Malik,J. T. Bigger,G. Breithardt,Sergio Cerutti,Richard J. Cohen,Philippe Coumel,Ernest L. Fallen,H.L. Kennedy,Robert E. Kleiger,Federico Lombardi,Alberto Malliani,Arthur J. Moss,Jeffrey N. Rottman,Georg Schmidt,Peter J. Schwartz,D.H. Singer +16 more
Journal ArticleDOI
Heart rate variability. Standards of measurement, physiological interpretation, and clinical use
Marek Malik,J. Thomas Bigger,A. John Camm,Robert E. Kleiger,Alberto Malliani,Arthur J. Moss,Peter J. Schwartz +6 more
Journal ArticleDOI
Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control
TL;DR: It is shown that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz.
Journal ArticleDOI
Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.
Massimo Pagani,Federico Lombardi,Stefano Guzzetti,Ornella Rimoldi,Raffaello Furlan,Paolo Pizzinelli,Giulia Sandrone,Gabriella Malfatto,Simonetta Dell’Orto,E Piccaluga +9 more
TL;DR: The spontaneous beat-to-beat oscillation in R-R interval during control recumbent position, 90° upright tilt, controlled respiration and acute and chronic β-adrenergic receptor blockade was analyzed, indicating that sympathetic nerves to the heart are instrumental in the genesis of low-frequency oscillations in R -R interval.
Journal ArticleDOI
Decreased heart rate variability and its association with increased mortality after acute myocardial infarction
Robert E. Kleiger,Robert E. Kleiger,Robert E. Kleiger,J. Philip Miller,J. Philip Miller,J. Philip Miller,J.Thomas Bigger,J.Thomas Bigger,J.Thomas Bigger,Arthur J. Moss,Arthur J. Moss,Arthur J. Moss +11 more
TL;DR: HR variability remained a significant predictor of mortality after adjusting for clinical, demographic, other Holter features and ejection fraction, and a hypothesis to explain this finding is that decreased HR variability correlates with increased sympathetic or decreased vagal tone, which may predispose to ventricular fibrillation.