M
Mari Kirsten
Researcher at University of Pretoria
Publications - 6
Citations - 1291
Mari Kirsten is an academic researcher from University of Pretoria. The author has contributed to research in topics: Rotavirus vaccine & Rotavirus. The author has an hindex of 5, co-authored 6 publications receiving 1194 citations.
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Journal ArticleDOI
Effect of human rotavirus vaccine on severe diarrhea in African infants.
Shabir A. Madhi,Nigel A. Cunliffe,Duncan Steele,Desiree Witte,Mari Kirsten,Cheryl Louw,Bagrey Ngwira,John C. Victor,Paul Gillard,Brigitte Cheuvart,Htay Htay Han,Kathleen M. Neuzil +11 more
TL;DR: Human rotvirus vaccine significantly reduced the incidence of severe rotavirus gastroenteritis among African infants during the first year of life.
Journal ArticleDOI
Intralesional bleomycin injection (IBI) treatment for haemangiomas and congenital vascular malformations.
TL;DR: IBI is an effective treatment in haemangiomas and vascular malformation lesions, obviating the need for invasive primary surgery or systemic treatment regimens in 80% of cases, and allowing for limited need of secondary surgical or adjunctive procedures in cases with a moderate result.
Journal ArticleDOI
Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial
A.D. Steele,Kathleen M. Neuzil,Nigel A. Cunliffe,Shabir A. Madhi,P. Bos,Bagrey Ngwira,Desiree Witte,Stacy Todd,Cheryl Louw,Mari Kirsten,Sanet Aspinall,Leen Jan Van Doorn,Alain Bouckenooghe,P.V. Suryakiran,Htay Htay Han +14 more
TL;DR: Rotarix™ vaccine demonstrated efficacy against severe gastroenteritis caused by diverse circulating rotavirus types, adding to a growing body of evidence supporting heterotypic protection provided by Rotarix’.
Journal ArticleDOI
Efficacy and immunogenicity of two or three dose rotavirus-vaccine regimen in South African children over two consecutive rotavirus-seasons: a randomized, double-blind, placebo-controlled trial.
Shabir A. Madhi,Mari Kirsten,Cheryl Louw,P. Bos,Sanet Aspinall,Alain Bouckenooghe,Kathleen M. Neuzil,A.D. Steele +7 more
TL;DR: Rarix is associated with significant reductions in severe gastroenteritis episodes through 2 years of life among South African children, and further research is needed to determine the optimal dosing schedule of Rotarix in providing long-term protection against rotavirus illness in African children.
Journal ArticleDOI
Evaluation of Intussusception After Oral Monovalent Rotavirus Vaccination in South Africa.
Michelle J. Groome,Michelle J. Groome,Jacqueline E. Tate,Marion Arnold,Marion Arnold,Milind Chitnis,Sharon Cox,Corné de Vos,Mari Kirsten,Susanna M. le Grange,Jerome Loveland,Sello Machaea,Ashwini Maharaj,Nick Andrews,Shabir A. Madhi,Shabir A. Madhi,Umesh D. Parashar +16 more
TL;DR: The risk of intussusception in the 21 days after the first or second dose of RV1 was not higher than the background risk among South Africa infants.