M
Marilyn C. Roberts
Researcher at University of Washington
Publications - 255
Citations - 19157
Marilyn C. Roberts is an academic researcher from University of Washington. The author has contributed to research in topics: Tetracycline & Plasmid. The author has an hindex of 61, co-authored 250 publications receiving 16668 citations. Previous affiliations of Marilyn C. Roberts include University of Victoria & Tufts University.
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Journal ArticleDOI
Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance
Ian Chopra,Marilyn C. Roberts +1 more
TL;DR: Changing the use of tetracyclines in human and animal health as well as in food production is needed if this class of broad-spectrum antimicrobials through the present century is to continue to be used.
Journal ArticleDOI
ResFinder 4.0 for predictions of phenotypes from genotypes.
Valeria Bortolaia,Rolf Sommer Kaas,Etienne Ruppé,Marilyn C. Roberts,Stefan Schwarz,Vincent Cattoir,Alain Philippon,Rosa Lundbye Allesøe,Rosa Lundbye Allesøe,Ana-Rita Rebelo,Alfred Ferrer Florensa,Linda Fagelhauer,Trinad Chakraborty,Bernd Neumann,Guido Werner,Jennifer K. Bender,Kerstin Stingl,Minh Ngoc Nguyen,Jasmine Coppens,Basil Britto Xavier,Surbhi Malhotra-Kumar,Henrik Westh,Henrik Westh,Mette Pinholt,Muna F. Anjum,Nicholas A. Duggett,Isabelle Kempf,Suvi Nykäsenoja,Satu Olkkola,Kinga Wieczorek,Ana Amaro,Lurdes Clemente,Joël Mossong,Serge Losch,Catherine Ragimbeau,Ole Lund,Frank Møller Aarestrup +36 more
TL;DR: WGS-based AST using ResFinder 4.0 provides in silico antibiograms as reliable as those obtained by phenotypic AST at least for the bacterial species/antimicrobial agents of major public health relevance considered.
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Update on acquired tetracycline resistance genes
TL;DR: New conjugative transposons, carrying different ribosomal protection tet genes, have been identified and an increase in the number of antibiotic resistance genes linked to tet genes has been found and whether these new elements may help to spread the tet genes they carry to a wider bacterial host range is discussed.
Journal ArticleDOI
Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants.
Marilyn C. Roberts,Joyce A. Sutcliffe,Patrice Courvalin,Lars Bogø Jensen,Julian I. Rood,Helena Seppälä +5 more
TL;DR: The usage of the newer macrolides has increased dramatically over the last few years, which has led to increased exposure of bacterial populations to macrolide resistance, and the nomenclature for these genes has varied and has been inconsistent.
Journal ArticleDOI
Mechanisms of antibiotic resistance
TL;DR: The efficiency of antibiotics is compromised by a growing number of antibiotic-resistant pathogens and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public.