M
Marjorie B. Lees
Researcher at Harvard University
Publications - 113
Citations - 67029
Marjorie B. Lees is an academic researcher from Harvard University. The author has contributed to research in topics: Myelin proteolipid protein & Proteolipid protein 1. The author has an hindex of 41, co-authored 113 publications receiving 64208 citations. Previous affiliations of Marjorie B. Lees include Duke University & Boston University.
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A simple method for the isolation and purification of total lipides from animal tissues.
TL;DR: In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.
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Preparation of lipide extracts from brain tissue.
TL;DR: A simple method is described for the preparation of extracts of total pure lipides from brain tissue by homogenizing the tissue with a chloroform-methanol mixture and washing free of non-lipide contaminants.
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Proteolipides, a new type of tissue lipoproteins; their isolation from brain.
Jordi Folch,Marjorie B. Lees +1 more
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Modification of the Lowry procedure for the analysis of proteolipid protein.
TL;DR: A modification of the Lowry procedure for the rapid and reliable analysis of proteolipid protein involves the addition of sodium dodecyl sulfate to dissolve the lipid-containing protein samples or to maintain the water-soluble apoprotein in solution.
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An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis
TL;DR: It is shown that changing a single amino acid in an antigenic peptide can significantly influence T cell differentiation and suggest that immune deviation may be one of the mechanisms by which APLs can inhibit an autoimmune disease.