M
Martin Güldenagel
Researcher at University of Bonn
Publications - 12
Citations - 2715
Martin Güldenagel is an academic researcher from University of Bonn. The author has contributed to research in topics: Connexin & Gap junction. The author has an hindex of 12, co-authored 12 publications receiving 2607 citations.
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Journal ArticleDOI
Structural and functional diversity of connexin genes in the mouse and human genome
Klaus Willecke,Jürgen Eiberger,Joachim Degen,Dominik Eckardt,Alessandro Romualdi,Martin Güldenagel,Urban Deutsch,Goran Söhl +7 more
TL;DR: This review compares currently identified connexin genes in both the mouse and human genome and discusses the functions of gap junctions deduced from targeted mouse mutants and human genetic disorders.
Journal ArticleDOI
Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.
Magalie A. Ravier,Martin Güldenagel,Anne Charollais,Asllan Gjinovci,Dorothée Caille,Goran Söhl,Claes B. Wollheim,Klaus Willecke,Jean-Claude Henquin,Paolo Meda +9 more
TL;DR: Data show that Cx36-dependent signaling is essential for the proper functioning of beta-cells, particularly for the pulsatility of [Ca(2+)](i) and insulin secretion during glucose stimulation.
Journal ArticleDOI
Visual Transmission Deficits in Mice with Targeted Disruption of the Gap Junction Gene Connexin36
Martin Güldenagel,Josef Ammermüller,Andreas Feigenspan,Barbara Teubner,Joachim Degen,Goran Söhl,Klaus Willecke,Reto Weiler +7 more
TL;DR: It is demonstrated that Cx36-containing gap junctions are essential for normal synaptic transmission within the rod pathway and not merely for distorted junctional transmission between AII amacrine cells and cone bipolar cells.
Journal ArticleDOI
Functional Expression of the Murine Connexin 36 Gene Coding for a Neuron-Specific Gap Junctional Protein
Barbara Teubner,Joachim Degen,Goran Söhl,Martin Güldenagel,Feliksas F. Bukauskas,E. B. Trexler,Vytas K. Verselis,C. I. De Zeeuw,C.G. Lee,C.A. Kozak,Elisabeth Petrasch-Parwez,Rolf Dermietzel,Klaus Willecke +12 more
TL;DR: The results suggest that Cx36 channels function as electrical synapses for transmission of electrical and metabolic signals between neurons in the central nervous system.
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Reduction of high‐frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36‐deficient mice
TL;DR: The findings indicate that Cx36 plays a role in the generation of certain forms of network synchronisation in the hippocampus, namely sharp wave‐ripple complexes and hypersynchronous epileptiform discharges.