Matthew J. Budoff

TL;DR: Current data suggest intermediate-risk patients may benefit most from further risk stratification with cardiac CT, as CAC testing is effective at identifying increased risk and in one study motivating effective behavioral changes, and Randomized clinical trials will help determine if selective use of cardiac CT in the intermediate- risk patient would lead to more appropriate use of pharmacologic therapy and improved clinical outcomes.

TL;DR: Overall, behavioral modification resulting in weight loss was lowest (19.8%) among those with CAC=0, and gradually increased with higher CAC scores, and a higher rate of adherences with statin therapy was observed in patients with higherCAC scores.

TL;DR: Higher plasma CXCL12 was associated with CVD risk factors and prevalent CVD as well as the hazard of incident MI and death in chronic kidney disease patients.

TL;DR: This study represents one of the first prospective multicenter, controlled clinical trials comparing 64-row CCTA to MPI in the same patients, demonstrating superior diagnostic accuracy of C CTA over myocardial perfusion single photon emission computed tomography (MPS) to reliably detect >50% and >70% stenosis in stable chest pain patients.

TL;DR: Family history of premature CHD is associated with enhanced development and progression of subclinical disease, independent of other risk factors, in a multiethnic, population-based study.