M
Mikael Mazighi
Researcher at University of Paris
Publications - 301
Citations - 12620
Mikael Mazighi is an academic researcher from University of Paris. The author has contributed to research in topics: Stroke & Modified Rankin Scale. The author has an hindex of 48, co-authored 249 publications receiving 9611 citations. Previous affiliations of Mikael Mazighi include Cleveland Clinic & University of Toronto.
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Journal ArticleDOI
Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke
Joseph P. Broderick,Yuko Y. Palesch,Andrew M. Demchuk,Sharon D. Yeatts,Pooja Khatri,Michael D. Hill,Edward C. Jauch,Tudor G Jovin,Bernard Yan,Frank L. Silver,Ruediger von Kummer,Carlos A. Molina,Bart M. Demaerschalk,Ronald F. Budzik,Wayne M. Clark,Osama O. Zaidat,Tim W. Malisch,Mayank Goyal,Wouter J. Schonewille,Mikael Mazighi,Stefan T. Engelter,Craig S. Anderson,Judith Spilker,Janice Carrozzella,Karla J Ryckborst,L. Scott Janis,Renee H Martin,Lydia D. Foster,Thomas A. Tomsick +28 more
TL;DR: The trial showed similar safety outcomes and no significant difference in functional independence with endovascular therapy after intravenous t-PA, as compared with intravenoust-PA alone.
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A transient ischaemic attack clinic with round-the-clock access (SOS-TIA): feasibility and effects.
Philippa C. Lavallée,Elena Meseguer,Halim Abboud,Lucie Cabrejo,Jean-Marc Olivot,Olivier Simon,Mikael Mazighi,Chantal Nifle,Philippe Niclot,Bertrand Lapergue,Isabelle F. Klein,Eric Brochet,Philippe Gabriel Steg,Guy Lesèche,Julien Labreuche,Pierre-Jean Touboul,Pierre Amarenco +16 more
TL;DR: Use of TIA clinics with 24-h access and immediate initiation of preventive treatment might greatly reduce length of hospital stay and risk of stroke compared with expected risk.
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Effect of Endovascular Contact Aspiration vs Stent Retriever on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion: The ASTER Randomized Clinical Trial.
Bertrand Lapergue,Raphaël Blanc,Benjamin Gory,Julien Labreuche,Alain Duhamel,Gaultier Marnat,Suzana Saleme,Vincent Costalat,Serge Bracard,Hubert Desal,Mikael Mazighi,Arturo Consoli,Michel Piotin +12 more
TL;DR: Among patients with ischemic stroke in the anterior circulation undergoing thrombectomy, first-line throm bectomy with contact aspiration compared with stent retriever did not result in an increased successful revascularization rate at the end of the procedure.
Journal ArticleDOI
Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase 3 trial
Pooja Khatri,Sharon D. Yeatts,Mikael Mazighi,Joseph P. Broderick,David S Liebeskind,Andrew M. Demchuk,Pierre Amarenco,Janice Carrozzella,Judith Spilker,Lydia D. Foster,Mayank Goyal,Michael D. Hill,Yuko Y. Palesch,Edward C. Jauch,E. Clarke Haley,Achala Vagal,Thomas A. Tomsick +16 more
TL;DR: Delays in time to angiographic reperfusion lead to a decreased likelihood of good clinical outcome in patients after moderate to severe stroke, and this association was validated in a preplanned analysis of data from the IMS III trial.
Journal ArticleDOI
Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN:
Nils Wahlgren,Tiago Moreira,Patrik Michel,Thorsten Steiner,Olav Jansen,Christophe Cognard,Heinrich Mattle,Wim H. van Zwam,Staffan Holmin,Turgut Tatlisumak,Jesper Petersson,Valeria Caso,Werner Hacke,Mikael Mazighi,Marcel Arnold,Urs Fischer,István Szikora,Laurent Pierot,Jens Fiehler,Jan Gralla,Franz Fazekas,Kennedy R. Lees +21 more
TL;DR: The original version of this consensus statement on mechanical thrombectomy was approved at the European Stroke Organisation-Karolinska Stroke Update conference in Stockholm, 16–18 November 2014 and has later, during 2015, been updated with new clinical trials data in accordance with a decision made at the conference.