M
Ming Zhang
Researcher at Sichuan University
Publications - 1156
Citations - 38278
Ming Zhang is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 74, co-authored 921 publications receiving 29116 citations. Previous affiliations of Ming Zhang include Beihang University & Beijing Institute of Technology.
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Proceedings ArticleDOI
LINE: Large-scale Information Network Embedding
TL;DR: A novel network embedding method called the ``LINE,'' which is suitable for arbitrary types of information networks: undirected, directed, and/or weighted, and optimizes a carefully designed objective function that preserves both the local and global network structures.
Proceedings ArticleDOI
LINE: Large-scale Information Network Embedding
TL;DR: LINE as discussed by the authors proposes a network embedding method called LINE, which is suitable for arbitrary types of information networks: undirected, directed, and/or weighted, and optimizes a carefully designed objective function that preserves both the local and global network structures.
Journal ArticleDOI
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Patrick J. Killela,Zachary J. Reitman,Yuchen Jiao,Chetan Bettegowda,Nishant Agrawal,Luis A. Diaz,Allan H. Friedman,Henry S. Friedman,Gary L. Gallia,Beppino C. Giovanella,Arthur P. Grollman,Tong-Chuan He,Yiping He,Ralph H. Hruban,George I. Jallo,Nils Mandahl,Alan K. Meeker,Fredrik Mertens,George J. Netto,B.K. Ahmed Rasheed,Gregory J. Riggins,Thomas A. Rosenquist,Mark Schiffman,Ie Ming Shih,Dan Theodorescu,Michael Torbenson,Victor E. Velculescu,Tian Li Wang,Nicolas Wentzensen,Laura D. Wood,Ming Zhang,Roger E. McLendon,Darell D. Bigner,Kenneth W. Kinzler,Bert Vogelstein,Nickolas Papadopoulos,Hai Yan +36 more
TL;DR: TERT and ATRX mutations were mutually exclusive, suggesting that these two genetic mechanisms confer equivalent selective growth advantages and provide a biomarker that may be useful for the early detection of urinary tract and liver tumors and aid in the classification and prognostication of brain tumors.
Journal ArticleDOI
The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Nicolas J. Llosa,Michael Cruise,Ada Tam,Elizabeth C. Wicks,Elizabeth M. Hechenbleikner,Janis M. Taube,Richard L. Blosser,Hongni Fan,Hao Wang,Brandon Luber,Ming Zhang,Nickolas Papadopoulos,Kenneth W. Kinzler,Bert Vogelstein,Cynthia L. Sears,Robert A. Anders,Drew M. Pardoll,Franck Housseau +17 more
TL;DR: The findings are the first to demonstrate a link between a genetically defined subtype of cancer and its corresponding expression of immune checkpoints in the tumor microenvironment, and suggest that blockade of specific checkpoints may be selectively efficacious in the MSI subset of colorectal cancer.
Journal ArticleDOI
A reference genome for common bean and genome-wide analysis of dual domestications
Jeremy Schmutz,Phillip E. McClean,Sujan Mamidi,G Albert Wu,Steven B. Cannon,Jane Grimwood,Jerry Jenkins,Shengqiang Shu,Qijian Song,Carolina Chavarro,Mirayda Torres-Torres,Valérie Geffroy,Samira Mafi Moghaddam,Dongying Gao,Brian Abernathy,Kerrie Barry,Matthew W. Blair,Mark A. Brick,Mansi Chovatia,Paul Gepts,David Goodstein,Michael D. Gonzales,Uffe Hellsten,David L. Hyten,Gaofeng Jia,James D. Kelly,Dave Kudrna,Rian Lee,Manon M.S. Richard,Phillip N. Miklas,Juan M. Osorno,Josiane Rodrigues,Vincent Thareau,Carlos A. Urrea,Mei Wang,Yeisoo Yu,Ming Zhang,Rod A. Wing,Perry B. Cregan,Daniel S. Rokhsar,Scott A. Jackson +40 more
TL;DR: 2 independent domestications from genetic pools that diverged before human colonization are confirmed and a set of genes linked with increased leaf and seed size are identified and combined with quantitative trait locus data from Mesoamerican cultivars.