N
Nico Nagelkerke
Researcher at Erasmus University Rotterdam
Publications - 27
Citations - 1818
Nico Nagelkerke is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Population & Onchocerciasis. The author has an hindex of 16, co-authored 27 publications receiving 1689 citations. Previous affiliations of Nico Nagelkerke include Erasmus University Medical Center & Wellcome Trust.
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Journal ArticleDOI
Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa.
Marieke J. van der Werf,Sake J. de Vlas,Simon Brooker,Caspar W. N. Looman,Nico Nagelkerke,J. Dik F. Habbema,Dirk Engels +6 more
TL;DR: It is concluded that schistosomiasis remains an important public health problem in sub-Saharan Africa and the mortality rates due to non-functioning kidney and haematemesis at 150000 and 130000 per year are estimated.
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Can ivermectin mass treatments eliminate onchocerciasis in Africa
M. Winnen,A. P. Plaisier,E. S. Alley,Nico Nagelkerke,G.J. van Oortmarssen,Boakye A. Boatin,J. D. F. Habbema +6 more
TL;DR: Elimination of onchocerciasis from most endemic foci in Africa appears to be possible, however, the requirements in terms of duration, coverage, and frequency of treatment may be prohibitive in highly endemic areas.
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Impact of ivermectin on onchocerciasis transmission: assessing the empirical evidence that repeated ivermectin mass treatments may lead to elimination/eradication in West-Africa
Gerard J. J. M. Borsboom,Boakye A. Boatin,Nico Nagelkerke,Hyacinthe Agoua,Komlan Akpoboua,E William Soumbey Alley,Yeriba Bissan,Alfons Renz,Laurent Yaméogo,Jan H. F. Remme,J. Dik F. Habbema +10 more
TL;DR: Ivermectin treatment has been very successful in eliminating onchocerciasis as a public health problem, however, the results presented in this paper make it almost certain that repeated ivermECTin mass treatment will not lead to the elimination of transmission of onchopocalypse from West Africa.
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Quitting Smoking May Restore Hematological Characteristics within Five Years
Elfrieke D Van Tiel,Petra H.M. Peeters,Henriette A. Smit,Nico Nagelkerke,A. Jeanne M. van Loon,Diederik E. Grobbee,H. Bas Bueno-de-Mesquita +6 more
TL;DR: A marked influence of current smoking habits on leukocyte counts and, to a lesser extent, on counts of erythrocytes and platelets is suggested and at least five years have to pass before changes in all hematological parameters may return to normal values.
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The HLA A2/6802 Supertype Is Associated with Reduced Risk of Perinatal Human Immunodeficiency Virus Type 1 Transmission
Kelly S. MacDonald,Joanne Embree,Nico Nagelkerke,Jose Castillo,Susie Ramhadin,Simon Njenga,Julius Oyug,JO Ndinya-Achola,Brian H. Barber,Job J. Bwayo,Francis A. Plummer,Francis A. Plummer +11 more
TL;DR: Decreased perinatal HIV-1 infection risk was strongly associated with possession of a functional cluster of related HLA alleles, called the A2/6802 supertype, which provides further evidence that HLA supertypes are associated with differential susceptibility to HIV- 1 transmission.