Journal ArticleDOI
Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa.
Marieke J. van der Werf,Sake J. de Vlas,Simon Brooker,Caspar W. N. Looman,Nico Nagelkerke,J. Dik F. Habbema,Dirk Engels +6 more
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TLDR
It is concluded that schistosomiasis remains an important public health problem in sub-Saharan Africa and the mortality rates due to non-functioning kidney and haematemesis at 150000 and 130000 per year are estimated.About:
This article is published in Acta Tropica.The article was published on 2003-05-01. It has received 867 citations till now. The article focuses on the topics: Schistosoma haematobium & Mortality rate.read more
Citations
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The immunobiology of schistosomiasis
TL;DR: Advances in the understanding of the immunology of schistosomiasis are summarized, with the bulk of the review reflecting the experimental focus on Schistosoma mansoni infection in mice.
Journal ArticleDOI
Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden.
Peter J. Hotez,Aruna Kamath +1 more
TL;DR: The overall burden of Africa's neglected tropical diseases may be severely underestimated, and a full assessment is an important step for disease control priorities, particularly in Nigeria and the Democratic Republic of Congo, where the greatest number of NTDs may occur.
Journal ArticleDOI
The genome of the blood fluke Schistosoma mansoni
Matthew Berriman,Brian J. Haas,Brian J. Haas,Philip T. LoVerde,R. Alan Wilson,Gary P. Dillon,Gustavo C. Cerqueira,Susan T. Mashiyama,Bissan Al-Lazikani,Luiza F. Andrade,Peter D. Ashton,Martin Aslett,Daniella Castanheira Bartholomeu,Daniella Castanheira Bartholomeu,Gaëlle Blandin,Conor R. Caffrey,Avril Coghlan,Richard M.R. Coulson,Tim A. Day,Arthur L. Delcher,Ricardo DeMarco,Ricardo DeMarco,Appoliniare Djikeng,Tina Eyre,John Gamble,Elodie Ghedin,Elodie Ghedin,Yong-Hong Gu,Christiane Hertz-Fowler,Hirohisha Hirai,Yuriko Hirai,Robin Houston,Alasdair Ivens,David A. Johnston,David A. Johnston,Daniela R. Lacerda,Daniela R. Lacerda,Camila D. S. Macedo,Paul McVeigh,Zemin Ning,Guilherme Oliveira,John P. Overington,Julian Parkhill,Mihaela Pertea,Raymond J. Pierce,Anna V. Protasio,Michael A. Quail,Marie-Adèle Rajandream,Jane Rogers,Mohammed Sajid,Steven L. Salzberg,Mario Stanke,Adrian Tivey,Owen White,Owen White,David L. Williams,David L. Williams,Jennifer R. Wortman,Jennifer R. Wortman,Wenjie Wu,Mostafa Zamanian,Adhemar Zerlotini,Claire M. Fraser-Liggett,Claire M. Fraser-Liggett,Barclay G. Barrell,Najib M. El-Sayed,Najib M. El-Sayed +66 more
TL;DR: Analysis of the 363 megabase nuclear genome of the blood fluke, the first sequenced flatworm, and a representative of the Lophotrochozoa offers insights into early events in the evolution of the animals, including the development of a body pattern with bilateral symmetry, and theDevelopment of tissues into organs.
Journal ArticleDOI
The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases.
Peter J. Hotez,Miriam Alvarado,María-Gloria Basáñez,Ian Bolliger,Rupert R A Bourne,Michel Boussinesq,Simon Brooker,Ami Shah Brown,Geoffrey Buckle,Christine M. Budke,Hélène Carabin,Luc E. Coffeng,Eric M. Fèvre,Thomas Fürst,Yara A. Halasa,Rashmi Jasrasaria,Nicole E. Johns,Jennifer Keiser,Charles H. King,Rafael Lozano,Michele E. Murdoch,Simon J. O’Hanlon,Sébastien D. S. Pion,Rachel L. Pullan,Kapa D. Ramaiah,Thomas Roberts,Donald S. Shepard,Jennifer L. Smith,Wilma A. Stolk,Eduardo A. Undurraga,Jürg Utzinger,Mengru Wang,Christopher J L Murray,Mohsen Naghavi +33 more
TL;DR: The publication of the Global Burden of Disease Study 2010 and the accompanying collection of Lancet articles in December 2012 provided the most comprehensive attempt to quantify the burden of almost 300 diseases, injuries, and risk factors, including neglected tropical diseases (NTDs).
Journal ArticleDOI
Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis
TL;DR: A raised estimate of 2-15% disability seems evident in different functional domains of a person with schistosomiasis, if confirmed in formal patient-preference studies, indicates a need to reassess the authors' priorities for treating this silent pandemic of schistOSomiasis.
References
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Book
An introduction to the bootstrap
Bradley Efron,Robert Tibshirani +1 more
TL;DR: This article presents bootstrap methods for estimation, using simple arguments, with Minitab macros for implementing these methods, as well as some examples of how these methods could be used for estimation purposes.
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An Introduction to the Bootstrap.
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Mortality by cause for eight regions of the world: Global Burden of Disease Study
TL;DR: The Global Burden of Disease Study (GBD) used various data sources and made corrections for miscoding of important diseases (eg, ischaemic heart disease) to estimate worldwide and regional cause-of-death patterns in 1990, and the estimates by cause provide a foundation for a more informed debate on public-health priorities.
Journal ArticleDOI
The global status of schistosomiasis and its control.
TL;DR: There is need for increased support for schistosomiasis control in the most severely affected countries, which are among the least developed whose health systems face difficulties to provide basic care at the primary health level.