Ram H. Datar

TL;DR: It is reported here that microcantilevers of different geometries have been used to detect two forms of prostate-specific antigen over a wide range of concentrations from 0.2 ng/ml to 60 μg/ml in a background of human serum albumin and human plasminogen at 1 mg/ml, making this a clinically relevant diagnostic technique for prostate cancer.

TL;DR: This is the first evidence of the existence of the putative stem-like phenotype within the DTC in bone marrow in early breast cancer patients and most individual DTC showed such phenotype.

TL;DR: Development of a parylene membrane microfilter device for single stage capture and electrolysis of circulating tumor cells (CTCs) in human blood, and the potential of this device to allow genomic analysis is presented.

TL;DR: A novel parylene membrane filter-based portable microdevice for size-based isolation with high recovery rate and direct on-chip characterization of captured CTC from human peripheral blood has the potential to enable routine CTC analysis in the clinical setting for the effective management of cancer patients.

TL;DR: The origin of motion lies in the interplay between changes in configurational entropy and intermolecular energetics induced by specific biomolecular interactions, and by controlling entropy change during DNA hybridization, the direction of cantilever motion can be manipulated.