Ramzi M. Kafoury

TL;DR: Evidence shows that inhibition of RAAS positively influences vascular remodeling thus improving CVD outcomes, and the need to rethink and rediscover new RAAS inhibitors is shared.

TL;DR: Exposure of cultured human bronchial epithelial cells to the ozonized 1-palmitoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine product resulted in a 113 +/- 11% increase in the amounts of tritiated platelet-activating factor released apically, suggesting LOP-dependent release of proinflammatory mediators may play an important role in the early inflammatory response seen during exposure to ozone.

TL;DR: The results suggest that biologically relevant concentrations of LOP activate PLA2, PLC, and PLD in the airway epithelial cell, a primary target to ozone exposure, and may play a role in the development of lung inflammation during ozone exposure.

TL;DR: Six of the commonly used surface coating agents are cytotoxic, especially those surfactants with long aliphatic chains, both cationic (cetyltrimethylammonium bromide, oleylamine, tetraoctylammonia bromides, and hexadecylamine) and anionic (sodium dodecylsulfate).

TL;DR: This article is intended to emphasize the potentially dangerous effects to the human respiratory system if inadequate measures are used in the manufacture, handling, and preparation and applications of CNP or CNP-based products.