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Rebecca Nagy
Researcher at Ohio State University
Publications - 65
Citations - 4948
Rebecca Nagy is an academic researcher from Ohio State University. The author has contributed to research in topics: Cancer & Thyroid cancer. The author has an hindex of 27, co-authored 56 publications receiving 4454 citations. Previous affiliations of Rebecca Nagy include The Ohio State University Wexner Medical Center.
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Journal ArticleDOI
The role of microRNA genes in papillary thyroid carcinoma
Hulling He,Krystian Jazdzewski,W. G. Li,Sandya Liyanarachchi,Rebecca Nagy,Stefano Volinia,George A. Calin,Chang Gong Liu,Kaarle Franssila,Saul Suster,Richard T. Kloos,Carlo M. Croce,Albert de la Chapelle +12 more
TL;DR: It is concluded that up-regulation of several miRs and regulation of KIT are involved in PTC pathogenesis, and that sequence changes in genes targeted by miRNAs can contribute to their regulation.
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Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
Julius Gudmundsson,Patrick Sulem,Daniel F. Gudbjartsson,Jon G. Jonasson,Asgeir Sigurdsson,Jon Thor Bergthorsson,Huiling He,Thorarinn Blondal,Frank Geller,Margret Jakobsdottir,Droplaug N Magnusdottir,Sigurborg Matthiasdottir,Simon N. Stacey,Oskar B Skarphedinsson,Hafdis T. Helgadottir,W. G. Li,Rebecca Nagy,Esperanza Aguillo,Eduardo Faure,Enrique Prats,Berta Saez,Mariano Martinez,Gudmundur I. Eyjolfsson,Unnur S. Bjornsdottir,Hilma Holm,Hilma Holm,Kristleifur Kristjansson,Michael L. Frigge,Hoskuldur Kristvinsson,Jeffrey R. Gulcher,Thorvaldur Jonsson,Thorunn Rafnar,Hannes Hjartarsson,Jose I. Mayordomo,Albert de la Chapelle,Jon Hrafnkelsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Augustine Kong,Kari Stefansson,Kari Stefansson +40 more
TL;DR: Two common variants, located on 9q22.33 and 14q13.3, are shown to be associated with thyroid cancer, and both risk alleles are associated with low concentrations of thyroid stimulating hormone (TSH) and high concentration of triiodothyronine (T3).
Journal ArticleDOI
Highly penetrant hereditary cancer syndromes.
TL;DR: In this review, 10 of the more highly penetrant cancer syndromes are considered, with emphasis on those predisposing to breast, colon, and/or endocrine neoplasia, as well as their underlying genetic defects.
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Essential Elements of Genetic Cancer Risk Assessment, Counseling, and Testing: Updated Recommendations of the National Society of Genetic Counselors
Bronson D. Riley,Julie O. Culver,Cécile Skrzynia,Leigha Senter,June A. Peters,Josephine Wagner Costalas,Faith Callif-Daley,Sherry C. Grumet,Katherine S. Hunt,Rebecca Nagy,Wendy McKinnon,Nancie Petrucelli,Robin L. Bennett,Angela Trepanier +13 more
TL;DR: These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of counseling at-risk individuals through genetic cancer risk assessment with or without genetic testing.
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Mutations in U4atac snRNA, a Component of the Minor Spliceosome, in the Developmental Disorder MOPD I
Huiling He,Sandya Liyanarachchi,Keiko Akagi,Rebecca Nagy,Jingfeng Li,Rosemary C. Dietrich,W. G. Li,Nikhil Sebastian,Bernard Wen,Baozhong Xin,Jarnail Singh,Pearlly S. Yan,Hansjuerg Alder,Eric Haan,Eric Haan,Dagmar Wieczorek,Beate Albrecht,Erik G. Puffenberger,Heng Wang,Judith A. Westman,Richard A. Padgett,David E. Symer,Albert de la Chapelle +22 more
TL;DR: It is shown that a gene encoding U4atac snRNA, a component of the minor U12-dependent spliceosome, is mutated in individuals with microcephalic osteodysplastic primordial dwarfism type I, a severe developmental disorder characterized by extreme intrauterine growth retardation and multiple organ abnormalities.