Josephine Wagner Costalas

TL;DR: These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of counseling at-risk individuals through genetic cancer risk assessment with or without genetic testing.

TL;DR: These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of identifying at-risk individuals through cancer risk assessment with or without genetic testing.

TL;DR: Probands who are BRCA1‐ or BRCa2‐positive are more likely to experience difficulty and distress with the communication of their test results to family members, and individuals who were carriers or tested positive for a mutation in the B RCA1 orBRCA2 gene share their results more often with their relatives.

TL;DR: Evaluated constitutional DNA isolated from 83 individuals diagnosed with breast cancer and 93 diagnosed with ovarian cancer at any age provided evidence for the presence of a specific BRCA2 mutation which has its origins in both Jewish Ashkenazi and non-Jewish populations.

TL;DR: A communication skills-building intervention, based on Buckman's model of “Breaking Bad News,” was developed for use in the setting of genetic testing for BRCA1 and BRCa2 mutations.