Robert Wilson

TL;DR: Recommendations and recommendations on what samples should be used to detect pulmonary non-tuberculous mycobacterial infection and how to define lung disease attributable to NTM infection are presented.

TL;DR: The full guideline for the management of non-tuberculous mycobacterial pulmonary disease is published in Thorax and a summary of the recommendations and good practice points is provided.

TL;DR: It is demonstrated that defects in B cell memory subsets are associated with impaired humoral immune responses in HIV-1 patients who are receiving antiretroviral therapy and may be a contributory factor to the increased risk of invasive pneumococcal infection observed in HIV -1 infection.

TL;DR: It is shown that in a 48-h organ culture pneumolysin caused ciliary slowing and epithelial disruption in a dose-dependent manner down to 5 ng/ml, and there was no correlation between the ciliary slows produced by the culture filtrate and thatproduced by the autolysate of a particular strain, nor between ciliary slowed and the extent of autolysis or the serotype of the strain.

TL;DR: Reassuringly, resistance to clarithromycin and amikacin is rare in most species, and Tigecycline, cycloserine and clofazimine may be useful in the treatment of the most resistant species.