R
Roberto Colombo
Researcher at University of Milan
Publications - 19
Citations - 5452
Roberto Colombo is an academic researcher from University of Milan. The author has contributed to research in topics: Protein Carbonylation & Oxidative stress. The author has an hindex of 15, co-authored 19 publications receiving 5112 citations. Previous affiliations of Roberto Colombo include University of Siena.
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Journal ArticleDOI
Protein carbonyl groups as biomarkers of oxidative stress.
TL;DR: The usage of protein CO groups as biomarkers of oxidative stress has some advantages in comparison with the measurement of other oxidation products because of the relative early formation and the relative stability of carbonylated proteins.
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Protein carbonylation in human diseases.
TL;DR: Rapid recent progress in the identification of carbonylated proteins should provide new diagnostic (possibly pre-symptomatic) biomarkers for oxidative damage, and yield basic information to aid the establishment an efficacious antioxidant therapy.
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Protein carbonylation, cellular dysfunction, and disease progression
Isabella Dalle-Donne,Giancarlo Aldini,Marina Carini,Roberto Colombo,Ranieri Rossi,Aldo Milzani +5 more
TL;DR: Identification of specific carbonylated protein(s) functionally impaired and development of selective carbonyl blockers should lead to the definitive assessment of the causative, correlative or consequential role of protein carbonylation in disease onset and/or progression, possibly providing new therapeutic aproaches.
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S-glutathionylation in protein redox regulation.
TL;DR: Recent breakthroughs in the understanding of the potential role of protein S-glutathionylation in the redox regulation of signal transduction are described.
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Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics
Isabella Dalle-Donne,Andrea Scaloni,Daniela Giustarini,Eleonora Cavarra,Gianluca Tell,Giuseppe Lungarella,Roberto Colombo,Ranieri Rossi,Aldo Milzani +8 more
TL;DR: The study of oxidative/nitrosative modifications, investigated by redox proteomics, is contributing to establish a relationship between pathological hallmarks of disease and protein structural and functional abnormalities, enabling early detection of diseases.