R
Robin Hull
Researcher at National Institute for Biological Standards and Control
Publications - 15
Citations - 1733
Robin Hull is an academic researcher from National Institute for Biological Standards and Control. The author has contributed to research in topics: Virus & Simian immunodeficiency virus. The author has an hindex of 11, co-authored 15 publications receiving 1574 citations. Previous affiliations of Robin Hull include University of Hertfordshire.
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Journal ArticleDOI
A good practice guide to the administration of substances and removal of blood, including routes and volumes
Karl-Heinz Diehl,Robin Hull,David B. Morton,Rudolf Pfister,Yvon Rabemampianina,David Smith,Jean-Marc Vidal,Cor Van De Vorstenbosch +7 more
TL;DR: An initiative between the European Federation of Pharmaceutical Industries Associations and the European Centre for the Validation of Alternative Methods to provide the researcher in the safety evaluation laboratory with an up‐to‐date, easy‐to-use set of data sheets to aid in the study design process.
Journal ArticleDOI
Evolution of the Sabin Strain of Type 3 Poliovirus in an Immunodeficient Patient during the Entire 637-Day Period of Virus Excretion
TL;DR: There was a delay in the appearance of antigenic variants compared to sequential type 3 isolates from healthy vaccines, which could be one of the possible explanations for the long-term excretion of virus from the patient.
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Mechanisms of protection induced by attenuated simian immunodeficiency virus.
Richard Stebbings,Neil Almond,E. Jim Stott,Neil Berry,Alison Wade-Evans,Robin Hull,Jenny Lines,P. Silvera,Rebecca Sangster,T. Corcoran,J. Rose,K. Barry Walker +11 more
TL;DR: Data do not support the hypothesis that protection conferred by live attenuated SIV is mediated by the induction of vigorous T-cell responses upon rechallenge, and protection against superinfection via secondary cellular immune responses via secondary cell immune responses is conferred.
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Evaluation of a candidate human immunodeficiency virus type 1 (HIV-1) vaccine in macaques: effect of vaccination with HIV-1 gp120 on subsequent challenge with heterologous simian immunodeficiency virus-HIV-1 chimeric virus
E.J. Stott,Neil Almond,K. Kent,Barry Walker,Robin Hull,J. Rose,P. Silvera,Rebecca Sangster,T. Corcoran,Jenny Lines,K. Silvera,Paul A. Luciw,M. Murphy-Corb,P. Momin,C. Bruck +14 more
TL;DR: Despite strong immune responses to the vaccine there was no evidence that it protected against challenge with this chimeric virus, and the antigenic divergence between vaccine and challenge virus or the increased virulence of the challenge virus may be responsible for the inability of this vaccine to protect against infection by SHIV(SF33).
Journal ArticleDOI
Mechanisms of Protection Induced by Attenuated Simian Immunodeficiency Virus II. Lymphocyte Depletion Does Not Abrogate Protection
Richard Stebbings,Jim Stott,Neil Almond,Robin Hull,Jenny Lines,P. Silvera,Rebecca Sangster,T. Corcoran,J. Rose,Steve Cobbold,Frances Gotch,Andrew J. McMichael,Barry Walker +12 more
TL;DR: Attempting to deplete macaques of their CD8+ cells prior to challenge with wild-type SIVmac32H failed to abrogate the protection conferred by vaccination with pC8.