S
Sarandeep S.S. Boyanapalli
Researcher at Rutgers University
Publications - 12
Citations - 623
Sarandeep S.S. Boyanapalli is an academic researcher from Rutgers University. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 9, co-authored 11 publications receiving 546 citations.
Papers
More filters
Journal ArticleDOI
Epigenetic CpG demethylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells.
Limin Shu,Tin Oo Khor,Jong Hun Lee,Sarandeep S.S. Boyanapalli,Ying Huang,Tien-Yuan Wu,Constance Lay Lay Saw,Ka-Lung Cheung,Ah-Ng Tony Kong +8 more
TL;DR: Evidence is provided on the CpG demethylation ability of CUR on Neurog1 while activating its expression, suggesting a potential epigenetic modifying role for this phytochemical compound in human prostate cancer cells.
Journal ArticleDOI
“Curcumin, the King of Spices”: Epigenetic Regulatory Mechanisms in the Prevention of Cancer, Neurological, and Inflammatory Diseases
TL;DR: The current knowledge on the effect of curcumin in the treatment and/or prevention of inflammation, neurodegenerative diseases, and cancers by regulating histone deacetylases, histone acetyltransferases, and DNA methyltransferases is summarized.
Journal ArticleDOI
Nrf2 Knockout Attenuates the Anti-Inflammatory Effects of Phenethyl Isothiocyanate and Curcumin
Sarandeep S.S. Boyanapalli,Ximena Paredes-Gonzalez,Francisco Fuentes,Chengyue Zhang,Yue Guo,Doug Pung,Constance Lay Lay Saw,Ah-Ng Tony Kong +7 more
TL;DR: The results from qPCR, western blot, and ELISA analyses in macrophages indicate that Nrf2 plays an important role in the anti-inflammatory and antioxidative effects of PEITC and CUR, as observed by their decreased activities in NRF2–/– macrophage.
Journal ArticleDOI
Pharmacodynamics of Ginsenosides: Antioxidant Activities, Activation of Nrf2 and Potential Synergistic Effects of Combinations
Constance Lay Lay Saw,Anne Yuqing Yang,Anne Yuqing Yang,David Cheng,Sarandeep S.S. Boyanapalli,Zheng-Yuan Su,Tin Oo Khor,Song Gao,Jing-Rong Wang,Zhi Hong Jiang,Ah-Ng Tony Kong +10 more
TL;DR: It is shown that ginsenosides Rb1, Rg1, and 20S possess antioxidant activity, transcriptionally activating ARE as well as the potential of synergistic activities.
Journal ArticleDOI
In vivo pharmacodynamics of indole-3-carbinol in the inhibition of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: Involvement of Nrf2 and cell cycle/apoptosis signaling pathways†
Tien-Yuan Wu,Constance Lay Lay Saw,Tin Oo Khor,Douglas Pung,Sarandeep S.S. Boyanapalli,Ah-Ng Tong Kong +5 more
TL;DR: It is demonstrated that the effectiveness of I3C as prostate cancer chemoprevention agent via up‐regulation of a novel Nrf2‐mediated anti‐oxidative stress pathway is demonstrated.