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Susan L. Prescott

Researcher at University of Western Australia

Publications -  367
Citations -  24020

Susan L. Prescott is an academic researcher from University of Western Australia. The author has contributed to research in topics: Allergy & Food allergy. The author has an hindex of 71, co-authored 342 publications receiving 20573 citations. Previous affiliations of Susan L. Prescott include Worldwide Universities Network & Telethon Institute for Child Health Research.

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Development of allergen-specific T-cell memory in atopic and normal children

TL;DR: The continuation of fetal allergen-specific Th2 responses during infancy is a defining feature of the inductive phase of atopic disease, and is associated with decreased capacity for production of the Th1 cytokine interferon y by atopic neonates.
Journal Article

Transplacental Priming of the Human Immune System to Environmental Allergens: Universal Skewing of Initial T Cell Responses Toward the Th2 Cytokine Profile

TL;DR: These findings imply that the key etiologic factor in atopic disease may not be the initial acquisition of allergen-specific Th2-skewed immunity per se, but instead may be the efficiency of immune deviation mechanisms, which in normal (nonatopic) individuals redirect these fetal immune responses toward the Th1 cytokine phenotype.
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Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: A randomized, controlled trial

TL;DR: These data suggest a potential reduction in subsequent infant allergy after maternal PUFA supplementation, and more detailed follow-up studies are required to establish the robustness of these findings and to ascertain their significance in relation to longer-term modification of allergic disease in children.