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Timothy C. Zhu

Researcher at University of Pennsylvania

Publications -  288
Citations -  6623

Timothy C. Zhu is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Photodynamic therapy & Photosensitizer. The author has an hindex of 44, co-authored 263 publications receiving 5954 citations. Previous affiliations of Timothy C. Zhu include Pennsylvania State University & Hospital of the University of Pennsylvania.

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A review of in-vivo optical properties of human tissues and its impact on PDT

TL;DR: The overall trend of the absorption spectra as a function of wavelength within a 95% confidence interval for various tissues in vivo is examined and the impact of optical properties on light fluence rate is discussed for various light application geometries including superficial, interstitial, and within a cavity.
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Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy.

TL;DR: Significant inter- and intra-prostatic variations in the tissue optical properties and MLu drug distribution are shown, suggesting that a real-time dosimetry measurement and feedback system for monitoring these values during treatment should be considered in future PDT studies.
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The role of photodynamic therapy (PDT) physics

TL;DR: The authors will review the current state of art in PDT research, with an emphasis in PDT physics, and foresee a merge of current separate areas of research in light production and delivery, PDT dosimetry, multimodality imaging, new photosensitizer development, and PDT biology into interdisciplinary combination of two to three areas.