W
Willeke F. Westendorp
Researcher at Albert Schweitzer Hospital
Publications - 19
Citations - 1042
Willeke F. Westendorp is an academic researcher from Albert Schweitzer Hospital. The author has contributed to research in topics: Stroke & Randomized controlled trial. The author has an hindex of 10, co-authored 16 publications receiving 824 citations. Previous affiliations of Willeke F. Westendorp include Leiden University Medical Center.
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Journal ArticleDOI
Post-stroke infection: a systematic review and meta-analysis
Willeke F. Westendorp,Paul J. Nederkoorn,Jan-Dirk Vermeij,Marcel G. W. Dijkgraaf,Diederik van de Beek +4 more
TL;DR: The need to prevent infections in patients with stroke is stressed, and pneumonia was associated with death, in a systematic review and meta-analysis of studies on post-stroke infection.
Journal ArticleDOI
Phenotypic variability in patients with ADA2 deficiency due to identical homozygous R169Q mutations
Joris M. van Montfrans,Esther A. R. Hartman,Kees P.J. Braun,Eric A. M. Hennekam,Elisabeth A. Hak,Paul J. Nederkoorn,Willeke F. Westendorp,Robbert G. M. Bredius,Wouter J.W. Kollen,Elisabeth H. Schölvinck,G. Elizabeth Legger,Isabelle Meyts,Adrian Liston,Klaske D. Lichtenbelt,Jacques C. Giltay,Gijs van Haaften,Gaby M. De Vries Simons,Helen L. Leavis,Cornelis J. G. Sanders,Marc Bierings,Stefan Nierkens,Marielle E. van Gijn +21 more
TL;DR: This case series revealed large phenotypic variability in patients with ADA2 deficiency though they were homozygous for the same R169Q mutation inCECR1 Disease modifiers, including epigenetic and environmental factors, thus seem important in determining the phenotype.
Journal ArticleDOI
Antibiotic therapy for preventing infections in patients with acute stroke.
Willeke F. Westendorp,Jan-Dirk Vermeij,Frederique H Vermeij,Heleen M. den Hertog,Diederik W.J. Dippel,Diederik van de Beek,Paul J. Nederkoorn +6 more
TL;DR: Assessment of the effectiveness and safety of preventive antibiotic therapy in people with ischaemic or haemorrhagic stroke found that antibiotics did reduce the risk of infection but did not reduce the number of dependent or deceased patients.
Journal ArticleDOI
Preventive antibiotics in stroke study: rationale and protocol for a randomised trial.
Paul J. Nederkoorn,Willeke F. Westendorp,Imke J. Hooijenga,Rob J. de Haan,Diederik W.J. Dippel,Frederique H Vermeij,Marcel G. W. Dijkgraaf,Jan M. Prins,Lodewijk Spanjaard,Diederik van de Beek +9 more
TL;DR: Whether the preventive use of the antibiotic ceftriaxone improves functional outcome in patients with stroke is investigated to determine whether the effect of antibiotic prophylaxis on clinical outcomes is improved.
Journal ArticleDOI
Antibiotic Therapy for Preventing Infections in People With Acute Stroke
Jan-Dirk Vermeij,Willeke F. Westendorp,Diederik W.J. Dippel,Diederik van de Beek,Paul J. Nederkoorn +4 more
TL;DR: This meta-analysis assessed whether preventive antibiotics in ischemic or hemorrhagic stroke can be improved by preventive antibiotic therapy and how to reduce the risk of a poor functional outcome and the overall infection rate.