W
William L. Nichols
Researcher at Mayo Clinic
Publications - 94
Citations - 4551
William L. Nichols is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Von Willebrand disease & Von Willebrand factor. The author has an hindex of 30, co-authored 93 publications receiving 4236 citations. Previous affiliations of William L. Nichols include University of Iowa & University of Vermont.
Papers
More filters
Journal ArticleDOI
Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor
J E Sadler,U. Budde,Jeroen Eikenboom,Emmanuel J. Favaloro,Frank Hill,Lars Holmberg,Jørgen Ingerslev,Christine A. Lee,David Lillicrap,P. M. Mannucci,Claudine Mazurier,Dominique Meyer,William L. Nichols,M. Nishino,Ian R. Peake,F. Rodeghiero,Reinhard Schneppenheim,Zaverio M. Ruggeri,A. Srivastava,Robert R. Montgomery,Augusto B. Federici +20 more
TL;DR: Six categories of von Willebrand disease correlate with important clinical features and therapeutic requirements, and certain VWD types, especially type 1 and type 2A, encompass several pathophysiologic mechanisms that sometimes can be distinguished by appropriate laboratory studies.
Journal ArticleDOI
von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA).
William L. Nichols,M. B. Hultin,Andra H. James,Marilyn J. Manco-Johnson,Robert R. Montgomery,Thomas L. Ortel,Margaret E. Rick,J. E. Sadler,Milton C. Weinstein,Barbara P. Yawn +9 more
TL;DR: This document summarizes needs for further research in VWF, VWD and bleeding disorders, including clinical research to obtain more objective information about bleeding symptoms, advancements in diagnostic and therapeutic tools, and enhancement in the education and training of clinicians and scientists in bleeding and thrombotic disorders.
Journal ArticleDOI
Lupus anticoagulant: An analysis of the clinical and laboratory features of 219 cases
TL;DR: To define clinical and laboratory characteristics of the lupus anticoagulant (LA), a review of the experience of subjects divided into those with the LA and the diagnosis of l upus erythematosus, and those with drug‐related lupUS syndromes.
Journal ArticleDOI
Acute leukemia with megakaryocytic differentiation: a study of 12 cases identified immunocytochemically
TL;DR: Acute leukemia with megakaryocytic differentiation may occur more frequently than previously recognized, may present with differing syndromic features, and can be identified by the use of specific antibody reagents and relatively simple immunocytochemical techniques.
Journal ArticleDOI
Acquired von Willebrand Disease
TL;DR: Therapeutic options include desmopressin and certain factor VIII concentrates that also contain vWF, and intravenous immunoglobulins have also shown some efficacy in the management of AvWD, especially cases associated with monoclonal gammopathies.