Margaret E. Rick

TL;DR: This document summarizes needs for further research in VWF, VWD and bleeding disorders, including clinical research to obtain more objective information about bleeding symptoms, advancements in diagnostic and therapeutic tools, and enhancement in the education and training of clinicians and scientists in bleeding and thrombotic disorders.

TL;DR: It is concluded that flow cytometric immunophenotyping may help establish the diagnosis of MDS, especially when morphology and cytogenetics are indeterminate.

TL;DR: A prospective MRI-based study to determine the prevalence of and evaluate possible risk factors for asymptomatic osteonecrosis of the hip in a sample of HIV-infected patients and hypothesized that additional patients may have developed clinically silent oste onecrosis.

TL;DR: Release of thrombospondin-1 from alpha-granules during activation provides positive feedback to promote efficient platelet aggregation and adhesion by overcoming the antithrombotic activity of physiologic NO.

TL;DR: HIV-infected patients are at approximately 100-fold greater risk of developing osteonecrosis than the general population and disease progression is slower in asymptomatic patients than in symptomatic patients.