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Xifang Zhu
Researcher at Huazhong Agricultural University
Publications - 35
Citations - 550
Xifang Zhu is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 19 publications receiving 330 citations.
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Journal ArticleDOI
Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways.
Jin-lun Lai,Yu-hui Liu,Chang Liu,Mingpu Qi,Rui-ning Liu,Xifang Zhu,Qiu-ge Zhou,Yingyu Chen,Aizhen Guo,Changmin Hu +9 more
TL;DR: Indirubin effectively suppressed LPS-induced inflammation via TLR4 abrogation mediated by the NF-kB and MAPK signaling pathways and may be useful for mastitis prophylaxis.
Journal ArticleDOI
Mycoplasma bovis NADH oxidase functions as both a NADH oxidizing and O2 reducing enzyme and an adhesin.
Gang Zhao,Hui Zhang,Xi Chen,Xifang Zhu,Yusi Guo,Chenfei He,Farhan Anwar Khan,Yingyu Chen,Changmin Hu,Huanchun Chen,Aizhen Guo +10 more
TL;DR: M. bovis NOX functions as both an active NADH oxidase and adhesin, and is therefore a potential virulence factor, and was further used to pan phage displaying lung cDNA library and fibronectin was determined to be potential ligand.
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Immunoproteomic identification of MbovP579, a promising diagnostic biomarker for serological detection of Mycoplasma bovis infection
Farhan Anwar Khan,Muhammad Faisal,Jin Chao,Kai Liu,Xi Chen,Gang Zhao,Harish Menghwar,Hui Zhang,Xifang Zhu,Muhammad Rasheed,Chenfei He,Changmin Hu,Yingyu Chen,Eric Baranowski,Huanchun Chen,Aizhen Guo +15 more
TL;DR: The novel antigen, MbovP579, was a sensitive and specific antigen for detection of antibodies in sera from both M. bovis-infected and vaccinated cattle and an ELISA based on rMbvP579 was established as a highly sensitive and Specific ELISA for the early diagnosis of M.bovis infection.
Journal ArticleDOI
Comparative Genomics of Mycoplasma bovis Strains Reveals That Decreased Virulence with Increasing Passages Might Correlate with Potential Virulence-Related Factors
Muhammad Rasheed,Muhammad Rasheed,Jingjing Qi,Xifang Zhu,He Chenfei,Harish Menghwar,Farhan Anwar Khan,Gang Zhao,Muhammad Zubair,Changmin Hu,Yingyu Chen,Huanchun Chen,Aizhen Guo +12 more
TL;DR: A subsequent collective bioinformatics analysis of paralogs, metabolic pathways, protein-protein interactions, secretory proteins, functionally conserved domains, and virulence-related factors identified 11 genes that likely contributed to the increased attenuation in the passaged strains, and these genes enrich the M. bovis genomics database.
Journal ArticleDOI
Genotype distribution of Chinese Mycoplasma bovis isolates and their evolutionary relationship to strains from other countries
Harish Menghwar,Chenfei He,Hui Zhang,Gang Zhao,Xifang Zhu,Farhan Anwar Khan,Muhammad Faisal,Muhammad Rasheed,Muhammad Zubair,Atta Muhammad Memon,Anne Ridley,Ian D. Robertson,Yingyu Chen,Aizhen Guo +13 more
TL;DR: The results suggest that ST-10 is an emerging clone of M. bovis, and it is hypothesized that the widespread distribution of this type is a result of global livestock movements.