Yan Yan

TL;DR: The latest research progress of the epidemiology, pathogenesis, and clinical characteristics of COVID-19 are summarized, and the current treatment and scientific advancements to combat the epidemic novel coronavirus are discussed.

TL;DR: The crystal structure of the N-terminal RNA binding domain of SARS-CoV-2 nucleocapsid protein is determined and several atomic resolution features are provided, guiding the design of novel antiviral agents specific targeting to Sars-Cov-2.

TL;DR: The crystal structure of the N-terminal RNA binding domain of SARS-CoV-2 nucleocapsid protein is determined and several atomic resolution features are provided, guiding the design of novel antiviral agents specific targeting to Sars-Cov-2.

TL;DR: Accurate and timely identification of clinical features in severe risks, and early and appropriate intervention can block disease progression are shown to be important indicators for early diagnosis and prediction of severe disease progression.

TL;DR: It is demonstrated that increased OSM expression is implicated in CRSwNP as a possible mechanism of TJs’ impairment, which can be further augmented following influenza infection via epithelial OSMexpression, possibly contributing to exacerbations.