Y
Yuan Gao
Researcher at Fourth Military Medical University
Publications - 12
Citations - 1579
Yuan Gao is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: microRNA & Hepatocellular carcinoma. The author has an hindex of 8, co-authored 9 publications receiving 1189 citations.
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Journal ArticleDOI
Circular RNA: A new star of noncoding RNAs
Shibin Qu,Xisheng Yang,Xiaolei Li,Jianlin Wang,Yuan Gao,Runze Shang,Wei Sun,Kefeng Dou,Haimin Li +8 more
TL;DR: Similar to miRNAs and long noncoding RNAs (lncRNAs), circRNAs are becoming a new research hotspot in the field of RNA and could be widely involved in the processes of life.
Journal ArticleDOI
Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelial-mesenchymal transition.
Yuan Gao,Bai Ruan,Weihui Liu,Jianlin Wang,Xisheng Yang,Zhuochao Zhang,Xia Li,Juanli Duan,Fuqing Zhang,Rui Ding,Kaishan Tao,Kefeng Dou +11 more
TL;DR: CD44 knockdown resulted in the decreased metastasis of HCC cells and the induction of MET by CD44 inhibition might be achieved, at least in part, by repressing the ERK/Snail pathway.
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MicroRNA-200a suppresses metastatic potential of Side Population cells in human hepatocellular carcinoma by decreasing ZEB2
Xisheng Yang,Jianlin Wang,Shibin Qu,Hongtao Zhang,Bai Ruan,Yuan Gao,Ben Ma,Xing Wang,Nan Wu,Xiaolei Li,Kefeng Dou,Haimin Li +11 more
TL;DR: Findings reveal that miR-200a suppresses metastasis of SP cells by downregulating ZEB2, and this was associated metastasis.
Journal ArticleDOI
MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis
Wei Sun,Zhuochao Zhang,Jianlin Wang,Runze Shang,Liang Zhou,Xing Wang,Juanli Duan,Bai Ruan,Yuan Gao,Bin Dai,Shibin Qu,Wei Liu,Rui Ding,Lin Wang,Desheng Wang,Kefeng Dou +15 more
TL;DR: It is found that miR-150 was significantly downregulated in hepatocellular carcinoma (HCC) tissues compared to adjacent noncancerous tissues and that the identified miR -150-GAB1-ERK axis is a potential therapeutic target for HCC.
Journal ArticleDOI
Fbxw7 regulates hepatocellular carcinoma migration and invasion via Notch1 signaling pathway.
Xing Wang,Juan Zhang,Liang Zhou,Wei Sun,Zhi-Gang Zheng,Peng Lu,Yuan Gao,Xisheng Yang,Zhuochao Zhang,Kaishan Tao,Kefeng Dou +10 more
TL;DR: The findings indicate that Fbxw7 can be used as a prognostic marker; it has an important role in HCC progression and inhibits HCC cell migration and invasion through the Notch1 signaling pathway.