Z
Zhen Pan
Researcher at Fudan University
Publications - 10
Citations - 946
Zhen Pan is an academic researcher from Fudan University. The author has contributed to research in topics: PLGA & Tissue engineering. The author has an hindex of 10, co-authored 10 publications receiving 773 citations.
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Journal ArticleDOI
Poly(lactide-co-glycolide) porous scaffolds for tissue engineering and regenerative medicine
Zhen Pan,Jiandong Ding +1 more
TL;DR: In the latest decade, some facile fabrication approaches at room temperature were put forward; more appropriate pore structures were designed and achieved; the mechanical properties were investigated both for dry and wet scaffolds and the effects of pore size and porosity on in vitro biodegradation were revealed.
Journal ArticleDOI
Control of cell nucleus shapes via micropillar patterns.
TL;DR: It is demonstrated that the shapes of cell nuclei could be regulated by the appropriate micropillar patterns, and some unusual nucleus shapes of BMSCs have been achieved, such as square, cross, dumbbell, and asymmetric sphere-protrusion.
Journal ArticleDOI
The effects of pore size in bilayered poly(lactide-co-glycolide) scaffolds on restoring osteochondral defects in rabbits.
TL;DR: The concept that the effects of pore size on osteochondral repair should be taken into consideration during scaffold design for tissue engineering is supported.
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Effect of porosities of bilayered porous scaffolds on spontaneous osteochondral repair in cartilage tissue engineering
TL;DR: This study illustrates unambiguously that cartilage tissue engineering allows for a wide range of scaffold porosity, yet some porosity group is optimal, and it is revealed that the biomechanical matching with the natural composite tissue should be taken into consideration in the design of practical biomaterials.
Journal ArticleDOI
Enhancing the bioactivity of Poly(lactic-co-glycolic acid) scaffold with a nano-hydroxyapatite coating for the treatment of segmental bone defect in a rabbit model.
De-Xin Wang,Yao He,Long Bi,Zehua Qu,Ji-Wei Zou,Zhen Pan,Junjun Fan,Liang Chen,Xin Dong,Xiangnan Liu,Guoxian Pei,Jiandong Ding +11 more
TL;DR: N nano-hydroxyapatite (nHA) was coated on the interior surfaces of PLGA scaffolds in order to facilitate in vivo bone defect restoration using biomimetic ceramics while keeping the polyester skeleton of the scaffolds.