Z
Zhongyu Jiang
Researcher at Chinese Academy of Sciences
Publications - 16
Citations - 861
Zhongyu Jiang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 12 publications receiving 357 citations. Previous affiliations of Zhongyu Jiang include University of Science and Technology of China.
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Journal ArticleDOI
Engineered nanomedicines with enhanced tumor penetration
Jianxun Ding,Jinjin Chen,Liqian Gao,Zhongyu Jiang,Yu Zhang,Mingqiang Li,Qicai Xiao,Su Seong Lee,Xuesi Chen +8 more
TL;DR: The multifunctional transformable nanoparticles have emerged as an advanced generation of nanomedicine with superior tumor penetration capabilities and prospects for improving tumor penetration are discussed.
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Ultrasound-Augmented Mitochondrial Calcium Ion Overload by Calcium Nanomodulator to Induce Immunogenic Cell Death.
TL;DR: In this article, an acid-sensitive PEGdecorated CaCO3 nanoparticle incorporating curcumin (CUR; a Ca2+ enhancer) (PEGCaCUR) was prepared using a simple one-pot strategy.
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A Multichannel Ca 2+ Nanomodulator for Multilevel Mitochondrial Destruction-Mediated Cancer Therapy
TL;DR: In this paper, a multichannel calcium ion (Ca2+ ) nanomodulator (CaNMCUR+CDDP ) was developed by a facile one-pot strategy in a sealed container with in situ synthesized polydopamine (PDA) as a template.
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Spatiotemporally Targeted Nanomedicine Overcomes Hypoxia-Induced Drug Resistance of Tumor Cells after Disrupting Neovasculature.
Jinjin Chen,Zhongyu Jiang,Zhongyu Jiang,Weiguo Xu,Tianmeng Sun,Xiuli Zhuang,Jianxun Ding,Xuesi Chen,Xuesi Chen +8 more
TL;DR: A shell-stacked nanoparticle (SNP) was developed for co-encapsulation of a VDA combretastatin A-4 phosphate (CA4P) and a proteasome inhibitor bortezomib (BTZ) and significantly inhibited the growth of both the human A549 pulmonary adenocarcinoma xenograft model and patient-derived xenografted model of colon cancer in mice, providing a promising strategy for treating advanced cancers.
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Chiral Polypeptide Thermogels Induce Controlled Inflammatory Response as Potential Immunoadjuvants
TL;DR: The results indicated that the chiral polypeptide thermogels could induce a controllable inflammatory response in vivo and exhibit great potential as an efficient adjuvant for immunotherapy.