Z
Zhuge Xi
Researcher at Academy of Military Medical Sciences
Publications - 22
Citations - 1048
Zhuge Xi is an academic researcher from Academy of Military Medical Sciences. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 5, co-authored 6 publications receiving 912 citations.
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Journal ArticleDOI
Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition.
TL;DR: The comparative analysis demonstrated that particle composition probably played a primary role in the cytotoxic effects of different nanoparticles, however, the potential genotoxicity might be mostly attributed to particle shape.
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Single-wall carbon nanotubes induce oxidative stress in rat aortic endothelial cells
Wen-Wen Cheng,Zhiqing Lin,Qiang Ceng,Bo-Fei Wei,Xian-Jun Fan,Hua-Shan Zhang,Wei Zhang,Honglian Yang,Huanliang Liu,Jun Yan,Lei Tian,Bencheng Lin,Shu-Mao Ding,Zhuge Xi +13 more
TL;DR: It was found that as SWCNT concentration increased, so did the stress protein, heme oxygenase-1 (HO-1), expression levels, and these changes may induce RAEC damage, and result in many serious diseases.
Journal Article
The effects of DNA damage induced by acetaldehyde
Zhuge Xi,Fu-Huan Chao,Danfeng Yang,Yong-mei Sun,Li Guanxian,Huashan Zhang,Wei Zhang,Yu-hua Yang,Huanliang Liu +8 more
TL;DR: The animal experiment shows that acetaldehyde can cause the oxidative DNA damage of rat lung tissues, which suggests thatacetaldehyde have the potential genotoxicity and its chemical mechanism is relative to the crosslinks and oxidation with DNA.
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Biodistribution of single-walled carbon nanotubes in rats
TL;DR: A generally adoptable tracing method for studying the biodistribution of SWCNTs (single walled carbon nanotubes) in vivo and the 125I labelling method is reliable and effective and affords a quantitative analysis of CNTs accumulated in animal tissues.
Journal ArticleDOI
Intestinal toxicity of micro- and nano-particles of foodborne titanium dioxide in juvenile mice: Disorders of gut microbiota-host co-metabolites and intestinal barrier damage.
Jun Yan,Qi Chen,Lei Tian,Kang Li,Wen Qing Lai,Liping Bian,Jie Han,Rui Jia,Xiaohua Liu,Zhuge Xi +9 more
TL;DR: In this article , the authors used the microbiome and targeted metabolomics to explore the potential mechanism of intestinal toxicity of foodborne TiO2 micro-/nanoparticles after oral exposure for 28 days in juvenile mice.