Benito Juárez Autonomous University of Oaxaca

About: Benito Juárez Autonomous University of Oaxaca is a education organization based out in Oaxaca City, Mexico. It is known for research contribution in the topics: Cancer & Gene. The organization has 438 authors who have published 446 publications receiving 3836 citations. The organization is also known as: Benito Juarez Autonomous University of Oaxaca.

Participation: the ascendancy of a buzzword in the neo-liberal era

Abstract: Participation was originally conceived as part of a counter-hegemonic approach to radical social transformation and, as such, represented a challenge to the status quo Paradoxically, throughout the 1980s and 1990s, ‘participation’ gained legitimacy within the institutional development world to the extent of achieving buzzword status The precise manipulations required to convert a radical proposal into something that could serve the neo-liberal world order led to participation's political decapitation Reduced to a series of methodological packages and techniques, participation would slowly lose its philosophical and ideological meaning In order to make the approach and methodology serve counter-hegemonic processes of grassroots resistance and transformation, these meanings desperately need to be recovered This calls for participation to be re-articulated within broader processes of social and political struggle in order to facilitate the recovery of social transformation in the world of twenty-first c

Ecological niche structure and rangewide abundance patterns of species.

Abstract: Spatial abundance patterns across species' ranges have attracted intense attention in macroecology and biogeography. One key hypothesis has been that abundance declines with geographical distance from the range centre, but tests of this idea have shown that the effect may occur indeed only in a minority of cases. We explore an alternative hypothesis: that species' abundances decline with distance from the centroid of the species' habitable conditions in environmental space (the ecological niche). We demonstrate consistent negative abundance–ecological distance relationships across all 11 species analysed (turtles to wolves), and that relationships in environmental space are consistently stronger than relationships in geographical space.

Building on Strength: Language and Literacy in Latino Families and Communities

Abstract: Building on Strength: Language and Literacy in Latino Families and CommunitiesAna Celia Zentella (editor), New York: Teachers College Press, and Covina, CA: California Association of Bilingual Education, 2005, 213 pages, US$2395 (paper)

Epigenetics in lung cancer diagnosis and therapy

Abstract: Lung cancer is the leading cause of cancer-related deaths worldwide. The initiation and progression of lung cancer is the result of the interaction between permanent genetic and dynamic epigenetic alterations. DNA methylation is the best studied epigenetic mark in human cancers. Altered DNA methylation in cancer was identified in 1983. Within 30 years of this discovery, DNA methylation inhibitors are used clinically to treat a variety of cancers, highlighting the importance of the epigenetic basis of cancer. In addition, histone modifications, nucleosome remodeling, and micro RNA (miRNA)-mediated gene regulation are also fundamental to tumor genesis. Distinct chromatin alterations occur in all stages of lung cancer, including initiation, growth, and metastasis. Therefore, stage-specific epigenetic changes can be used as powerful and reliable tools for early diagnosis of lung cancer and to monitor patient prognosis. Moreover, since epigenetic changes are dynamic and reversible, chromatin modifiers are promising targets for the development of more effective therapeutic strategies against cancer. This review summarizes the chromatin alterations in lung cancer, focusing on the diagnostic and therapeutic approaches targeting epigenetic modifications that could help to reduce the high case-fatality rate of this dreadful disease.