Institution
Bristol Royal Infirmary
Healthcare•Bristol, United Kingdom•
About: Bristol Royal Infirmary is a healthcare organization based out in Bristol, United Kingdom. It is known for research contribution in the topics: Population & Cancer. The organization has 5091 authors who have published 5688 publications receiving 197089 citations.
Topics: Population, Cancer, Randomized controlled trial, Mucin, Poison control
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors applied available incidence rates for hip fracture from various parts of the world to projected populations in 1990, 2025 and 2050 in order to estimate the numbers of hip fractures which might occur in each of the major continental regions.
Abstract: Hip fractures are recognized to be a major public health problem in many Western nations, most notably those in North America, Europe and Oceania. Incidence rates for hip fracture in other parts of the world are generally lower than those reported for these predominantly Caucasian populations, and this has led to the belief that osteoporosis represents less of a problem to the nations of Asia, South American and Africa. Demographic changes in the next 60 years, however, will lead to huge increases in the elderly populations of those countries. We have applied available incidence rates for hip fracture from various parts of the world to projected populations in 1990, 2025 and 2050 in order to estimate the numbers of hip fractures which might occur in each of the major continental regions. The projections indicate that the number of hip fractures occurring in the world each year will rise from 1.66 million in 1990 to 6.26 million by 2050. While Europe and North America account for about half of all hip fractures among elderly people today, this proportion will fall to around one quarter in 2050, by which time steep increases will be observed throughout Asia and Latin America. The results suggest that osteoporosis will truly become a global problem over the next half century, and that preventive strategies will be required in parts of the world where they are not currently felt to be necessary.
2,612 citations
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TL;DR: This study has shown that a stool form scale can be used to monitor change in intestinal function and such scales have utility in both clinical practice and research.
Abstract: Background: Stool form scales are a simple method of assessing intestinal transit rate but are not widely used in clinical practice or research, possibly because of the lack of evidence that they a...
2,345 citations
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TL;DR: Universal economic constraints in healthcare services dictate that further developments in total hip replacement will be governed by their cost-effectiveness, and computer-assisted surgery will contribute to reproducible and accurate placement of implants.
1,917 citations
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Haukeland University Hospital1, Uppsala University2, Karolinska Institutet3, University of Liverpool4, Humboldt University of Berlin5, Goethe University Frankfurt6, Southampton General Hospital7, Princess Alexandra Hospital8, Bristol Royal Infirmary9, University of Birmingham10, European Organisation for Research and Treatment of Cancer11, Katholieke Universiteit Leuven12
TL;DR: In this article, the authors compared the combination of perioperative chemotherapy and surgery compared with surgery alone for patients with initially resectable liver metastases from colorectal cancer.
1,741 citations
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TL;DR: Red blood cell transfusion in patients having cardiac surgery is strongly associated with both infection and ischemic postoperative morbidity, hospital stay, increased early and late mortality, and hospital costs.
Abstract: Background— Red blood cell transfusion can both benefit and harm. To inform decisions about transfusion, we aimed to quantify associations of transfusion with clinical outcomes and cost in patients having cardiac surgery. Methods and Results— Clinical, hematology, and blood transfusion databases were linked with the UK population register. Additional hematocrit information was obtained from intensive care unit charts. Composite infection (respiratory or wound infection or septicemia) and ischemic outcomes (myocardial infarction, stroke, renal impairment, or failure) were prespecified as coprimary end points. Secondary outcomes were resource use, cost, and survival. Associations were estimated by regression modeling with adjustment for potential confounding. All adult patients having cardiac surgery between April 1, 1996, and December 31, 2003, with key exposure and outcome data were included (98%). Adjusted odds ratios for composite infection (737 of 8516) and ischemic outcomes (832 of 8518) for transfuse...
1,132 citations
Authors
Showing all 5101 results
Name | H-index | Papers | Citations |
---|---|---|---|
Cyrus Cooper | 204 | 1869 | 206782 |
David T. Felson | 153 | 861 | 133514 |
Sheila Bingham | 136 | 519 | 67332 |
Stephen R. Bloom | 134 | 747 | 71493 |
Vineet Kumar | 123 | 1241 | 73909 |
Gareth J. Morgan | 109 | 1019 | 52957 |
Paul Dieppe | 105 | 618 | 53529 |
David J. Nutt | 104 | 995 | 45052 |
Andrew P. Halestrap | 99 | 236 | 37185 |
Stafford L. Lightman | 98 | 714 | 36735 |
Sydney Brenner | 95 | 340 | 54977 |
Christopher P. Denton | 95 | 675 | 42040 |
M. A. Ghatei | 90 | 410 | 36233 |
Chandan K. Sen | 90 | 416 | 30011 |
Nicholas A. Wright | 90 | 516 | 29037 |