Institution
Central and North West London NHS Foundation Trust
Healthcare•London, United Kingdom•
About: Central and North West London NHS Foundation Trust is a healthcare organization based out in London, United Kingdom. It is known for research contribution in the topics: Mental health & Population. The organization has 431 authors who have published 528 publications receiving 10826 citations.
Topics: Mental health, Population, Randomized controlled trial, Eating disorders, Psychological intervention
Papers published on a yearly basis
Papers
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Chelsea and Westminster Hospital NHS Foundation Trust1, Public Health England2, Central and North West London NHS Foundation Trust3, University College London4, Brighton and Sussex University Hospitals NHS Trust5, Central Manchester University Hospitals NHS Foundation Trust6, Imperial College Healthcare7, Hull York Medical School8, Barts Health NHS Trust9, University of Cambridge10, Guy's and St Thomas' NHS Foundation Trust11, Heart of England NHS Foundation Trust12, University of Liverpool13
TL;DR: In this high incidence population, daily tenofovir–emtricitabine conferred even higher protection against HIV than in placebo-controlled trials, refuting concerns that effectiveness would be less in a real-world setting.
1,472 citations
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TL;DR: A meta-analysis examining short-term effects of music therapy for depression found moderate-quality evidence of large effects favouring music therapy and TAU over TAU alone for both clinician-rated depressive symptoms and secondary outcomes.
Abstract: Background
Depression is a highly prevalent disorder associated with reduced social functioning, impaired quality of life, and increased mortality. Music therapy has been used in the treatment of a variety of mental disorders, but its impact on those with depression is unclear.
Objectives
To examine the efficacy of music therapy with standard care compared to standard care alone among people with depression and to compare the effects of music therapy for people with depression against other psychological or pharmacological therapies.
Search methods
CCDANCTR-Studies and CCDANCTR-References were searched on 7/11/2007, MEDLINE, PsycINFO, EMBASE, PsycLit, PSYindex, and other relevant sites were searched in November 2006. Reference lists of retrieved articles were hand searched, as well as specialist music and arts therapies journals.
Selection criteria
All randomised controlled trials comparing music therapy with standard care or other interventions for depression.
Data collection and analysis
Data on participants, interventions and outcomes were extracted and entered onto a database independently by two review authors. The methodological quality of each study was also assessed independently by two review authors. The primary outcome was reduction in symptoms of depression, based on a continuous scale.
Main results
Five studies met the inclusion criteria of the review. Marked variations in the interventions offered and the populations studied meant that meta-analysis was not appropriate. Four of the five studies individually reported greater reduction in symptoms of depression among those randomised to music therapy than to those in standard care conditions. The fifth study, in which music therapy was used as an active control treatment, reported no significant change in mental state for music therapy compared with standard care. Dropout rates from music therapy conditions appeared to be low in all studies.
Authors' conclusions
Findings from individual randomised trials suggest that music therapy is accepted by people with depression and is associated with improvements in mood. However, the small number and low methodological quality of studies mean that it is not possible to be confident about its effectiveness. High quality trials evaluating the effects of music therapy on depression are required.
483 citations
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TL;DR: The prevalence, aetiology, and management of depression and anxiety in patients with cancer is outlined to raise awareness among doctors of the need to address the psychiatric consequences of cancer.
Abstract: ### What you need to know
Advances in cancer treatments mean that half of people now diagnosed with cancer can expect to survive for at least 10 years,1 defining many cancers as long term conditions. Psychiatric illnesses such as depression and anxiety are common, but often neglected, complications of cancer, influencing quality of life, adherence to treatment, cancer survival, and treatment costs.23 Depression and anxiety affect up to 20% and 10% of patients with cancer respectively, regardless of the point in the cancer trajectory, and whether in curative or palliative treatment.4 Geographical variations in the diagnosis and treatment of depression or anxiety in cancer settings implies under-recognition of these problems.5 Depression is associated with poor adherence to cancer treatment and poor cancer survival,6 and the increased risk of suicide in all patients with cancer7 is a concern.
This clinical update outlines the prevalence, aetiology, and management of depression and anxiety in patients with cancer to raise awareness among doctors of the need to address the psychiatric consequences of cancer.
### Sources and selection criteria
We conducted tumour-specific and treatment-specific PubMed searches, and used NICE …
382 citations
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University College London1, University of Sussex2, Imperial College London3, The Advisory Board Company4, Royal Free London NHS Foundation Trust5, Central and North West London NHS Foundation Trust6, Cardiff University7, University of Liverpool8, Western General Hospital9, University of Edinburgh10, Barts Health NHS Trust11, Medical Research Council12, University of Cambridge13, King's College London14, North Manchester General Hospital15, Imperial College Healthcare16
TL;DR: These guidelines are aimed at clinical professionals directly involved with and responsible for the care of adults with HIV infection and at community advocates responsible for promoting the best interests and care of HIV-positive adults.
Abstract: The overall purpose of these guidelines is to provide guidance on best clinical practice in the treatment and management of adults with HIV infection with antiretroviral therapy (ART). The scope includes: (i) guidance on the initiation of ART in those previously naive to therapy; (ii)support of patients on treatment; (iii) management of patients experiencing virological failure; and (iv) recommendations in specific patient populations where other factors need to be taken into consideration. The guidelines are aimed at clinical professionals directly involved with and responsible for the care of adults with HIV infection and at community advocates responsible for promoting the best interests and care of HIV-positive adults. They should be read in conjunction with other published BHIVA guidelines.
366 citations
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TL;DR: In this article, the authors conducted 55 individual interviews and 8 focus groups with people recruited from UK-based long Covid patient support groups, social media and snowballing to document such patients' lived experience, including accessing and receiving healthcare and ideas for improving services.
Abstract: Approximately 10% of patients with Covid-19 experience symptoms beyond 3–4 weeks. Patients call this “long Covid”. We sought to document such patients’ lived experience, including accessing and receiving healthcare and ideas for improving services. We held 55 individual interviews and 8 focus groups (n = 59) with people recruited from UK-based long Covid patient support groups, social media and snowballing. We restricted some focus groups to health professionals since they had already self-organised into online communities. Participants were invited to tell their stories and comment on others’ stories. Data were audiotaped, transcribed, anonymised and coded using NVIVO. Analysis incorporated sociological theories of illness, healing, peer support, clinical relationships, access, and service redesign. Of 114 participants aged 27–73 years, 80 were female. Eighty-four were White British, 13 Asian, 8 White Other, 5 Black, and 4 mixed ethnicity. Thirty-two were doctors and 19 other health professionals. Thirty-one had attended hospital, of whom 8 had been admitted. Analysis revealed a confusing illness with many, varied and often relapsing-remitting symptoms and uncertain prognosis; a heavy sense of loss and stigma; difficulty accessing and navigating services; difficulty being taken seriously and achieving a diagnosis; disjointed and siloed care (including inability to access specialist services); variation in standards (e.g. inconsistent criteria for seeing, investigating and referring patients); variable quality of the therapeutic relationship (some participants felt well supported while others felt “fobbed off”); and possible critical events (e.g. deterioration after being unable to access services). Emotionally significant aspects of participants’ experiences informed ideas for improving services. Suggested quality principles for a long Covid service include ensuring access to care, reducing burden of illness, taking clinical responsibility and providing continuity of care, multi-disciplinary rehabilitation, evidence-based investigation and management, and further development of the knowledge base and clinical services. NCT04435041.
317 citations
Authors
Showing all 436 results
Name | H-index | Papers | Citations |
---|---|---|---|
Geoffrey Smith | 111 | 971 | 53218 |
Robert F. Miller | 65 | 631 | 18245 |
Stephanie Taylor | 63 | 275 | 15149 |
Glenn Waller | 62 | 384 | 12887 |
Alan A Montgomery | 55 | 255 | 15717 |
Alison D. Grant | 54 | 240 | 9830 |
Mike J. Crawford | 52 | 280 | 10060 |
Richard Gilson | 46 | 188 | 10678 |
Anne Lingford-Hughes | 46 | 201 | 8304 |
Paul Ramchandani | 44 | 153 | 8303 |
Ravindra K. Gupta | 38 | 144 | 6658 |
Ian Williams | 37 | 125 | 4061 |
Simon Edwards | 35 | 116 | 7687 |
John Green | 34 | 166 | 6508 |
Danielle Mercey | 28 | 70 | 2198 |