Institution
Colchester Hospital University NHS Foundation Trust
About: Colchester Hospital University NHS Foundation Trust is a based out in . It is known for research contribution in the topics: Tinnitus & Population. The organization has 200 authors who have published 165 publications receiving 5418 citations. The organization is also known as: Essex Rivers Healthcare NHS Trust & Essex Rivers Healthcare National Health Service Trust.
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TL;DR: This section contains the guidelines for adult BLS by lay rescuers and for the use of an automated external defibrillator (AED), which includes recognition of sudden cardiac arrest, the recovery position and management of choking.
1,486 citations
Guy's and St Thomas' NHS Foundation Trust1, John Radcliffe Hospital2, University of Nottingham3, Brigham and Women's Hospital4, ISMETT5, Banaras Hindu University6, Newton Wellesley Hospital7, Madras Institute of Orthopaedics and Traumatology8, University of the West Indies9, University of Michigan10, Sahlgrenska University Hospital11, Queen Mary University of London12, Aga Khan University13, University of Manchester14, Virginia Commonwealth University15, University of Padua16, Changi General Hospital17, King's College London18, Southampton General Hospital19, Texas Tech University Health Sciences Center20, McMaster University21, University Hospital Waterford22, Turku University Hospital23, University of Mainz24, Bezmialem Foundation University25, Colchester Hospital University NHS Foundation Trust26, Kent State University27, Guy's Hospital28, Cairo University29, Children's of Alabama30
TL;DR: The development of the STROCSS guideline (Strengthening the Reporting of Cohort Studies in Surgery), consisting of a 17-item checklist, is described and it is hoped its use will increase the transparency and reporting quality of such studies.
736 citations
TL;DR: The findings showed no evidence of a survival benefit with early treatment of relapse on the basis of a raised CA125 concentration alone, and therefore the value of routine measurement of CA125 in the follow-up of patients with ovarian cancer who attain a complete response after first-line treatment is not proven.
457 citations
TL;DR: TaTME appears to be an oncologically safe and effective technique for distal mesorectal dissection with acceptable short-term patient outcomes and good specimen quality.
Abstract: Objective: This study aims to report short-term clinical and oncological outcomes from the international transanal Total Mesorectal Excision (taTME) registry for benign and malignant rectal pathology. Background: TaTME is the latest minimally invasive transanal technique pioneered to facilitate difficult pelvic dissections. Outcomes have been published from small cohorts, but larger series can further assess the safety and efficacy of taTME in the wider surgical population. Methods: Data were analyzed from 66 registered units in 23 countries. The primary endpoint was "good-quality TME surgery." Secondary endpoints were short-term adverse events. Univariate and multivariate regression analyses were used to identify independent predictors of poor specimen outcome. Results: A total of 720 consecutively registered cases were analyzed comprising 634 patients with rectal cancer and 86 with benign pathology. Approximately, 67% were males with mean BMI 26.5 kg/m 2. Abdominal or perineal conversion was 6.3% and 2.8%, respectively. Intact TME specimens were achieved in 85%, with minor defects in 11% and major defects in 4%. R1 resection rate was 2.7%. Postoperative mortality and morbidity were 0.5% and 32.6% respectively. Risk factors for poor specimen outcome (suboptimal TME specimen, perforation, and/or R1 resection) on multivariate analysis were positive CRM on staging MRI, low rectal tumor <2 cm from anorectal junction, and laparoscopic transabdominal posterior dissection to <4 cm from anal verge. Conclusions: TaTME appears to be an oncologically safe and effective technique for distal mesorectal dissection with acceptable short-term patient outcomes and good specimen quality. Ongoing structured training and the upcoming randomized controlled trials are needed to assess the technique further.
354 citations
TL;DR: Large tumors in obese, diabetic male patients who smoke have the highest risk of anastomotic failure following Transanal Total Mesorectal Excision, and acknowledging such risk factors can guide appropriate consent and clinical decision-making that may reduce anastsomotic-related morbidity.
Abstract: Objective:To determine the incidence of anastomotic-related morbidity following Transanal Total Mesorectal Excision (TaTME) and identify independent risk factors for failure.Background:Anastomotic leak and its sequelae are dreaded complications following gastrointestinal surgery. TaTME is a recent t
256 citations
Authors
Showing all 200 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Michael R. Hamblin | 117 | 899 | 59533 |
| Anthony J. Handley | 36 | 111 | 10223 |
| Martin Walshaw | 33 | 92 | 3316 |
| Zeshaan N. Maan | 30 | 116 | 2895 |
| Neil J. Smart | 29 | 198 | 3031 |
| Alan Askari | 21 | 93 | 1714 |
| Saeed-Ul Hassan | 21 | 95 | 1125 |
| Joanne Patterson | 20 | 64 | 1380 |
| Don McFerran | 19 | 52 | 1279 |
| Marta Penna | 17 | 30 | 1337 |
| Darren Boone | 15 | 51 | 610 |
| Matthew G. Tutton | 15 | 28 | 1143 |
| P. Bennett | 14 | 28 | 1444 |
| Matthew E. Smith | 13 | 54 | 552 |
| Tan Arulampalam | 13 | 26 | 671 |