Institution
Derriford Hospital
Healthcare•Plymouth, United Kingdom•
About: Derriford Hospital is a healthcare organization based out in Plymouth, United Kingdom. It is known for research contribution in the topics: Population & Transplantation. The organization has 2892 authors who have published 3137 publications receiving 84438 citations.
Topics: Population, Transplantation, Randomized controlled trial, Mantle cell lymphoma, Poison control
Papers published on a yearly basis
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TL;DR: The contribution of constitutional factors, as demonstrated by antenatal bladder neck mobility, in the development of postpartum urinary stress incontinence is assessed.
154 citations
TL;DR: Increased compliance with an Enhanced Recovery After Surgery pathway is associated with improved clinical outcomes after resection for primary lung cancer and several elements, including early mobilization, appear to be more influential than others.
154 citations
TL;DR: In this article, mixed effects logistic regression was used to compare the following outcomes according to occurrence of severe hypertension, adjusting for allocated group and the influence of baseline factors: CHIPS primary (perinatal loss or high-level neonatal care for >48 hours) and secondary outcomes (serious maternal complications), birth weight 9 /L, elevated liver enzymes with symptoms, maternal length of stay ≥10 days, and maternal readmission before 6 weeks postpartum.
Abstract: To determine whether clinical outcomes differed by occurrence of severe hypertension in the international CHIPS trial (Control of Hypertension in Pregnancy Study), adjusting for the interventions of “less tight” (target diastolic blood pressure [dBP] 100 mm Hg) versus “tight” control (target dBP 85 mm Hg). In this post-hoc analysis of CHIPS data from 987 women with nonsevere nonproteinuric preexisting or gestational hypertension, mixed effects logistic regression was used to compare the following outcomes according to occurrence of severe hypertension, adjusting for allocated group and the influence of baseline factors: CHIPS primary (perinatal loss or high-level neonatal care for >48 hours) and secondary outcomes (serious maternal complications), birth weight 9 /L, elevated liver enzymes with symptoms, maternal length of stay ≥10 days, and maternal readmission before 6 weeks postpartum. Three hundred and thirty-four (34.1%) women in CHIPS developed severe hypertension that was associated with all outcomes examined except for maternal readmission ( P =0.20): CHIPS primary outcome, birth weight P 9 /L ( P =0.006), and prolonged hospital stay ( P =0.03). The association between severe hypertension and serious maternal complications was seen only in less tight control ( P =0.02). Adjustment for preeclampsia (464, 47.3%) did not negate the relationship between severe hypertension and the CHIPS primary outcome ( P P =0.005), delivery at P P P =0.02). Severe hypertension is a risk marker for adverse maternal and perinatal outcomes, independent of BP control or preeclampsia co-occurrence. Clinical Trial Registration— URL: http://pre-empt.cfri.ca/. Unique identifier: ISRCTN 71416914. URL: https://www.clinicaltrials.gov/. Unique identifier: NCT01192412.
152 citations
TL;DR: It is assumed that most human and animal melioidosis arises through exposure to contaminated soil or muddy water, although only 6% of human cases have a clear history of inoculation, and a further 0.5% of cases follow near-drowning.
151 citations
Derriford Hospital1, Hospital de Sant Pau2, University of Bonn3, University of Padua4, Sapienza University of Rome5, Aarhus University Hospital6, Ludwig Maximilian University of Munich7, Goethe University Frankfurt8, Hospital General Universitario Gregorio Marañón9, University College London10, University of Bologna11, Paris Diderot University12
TL;DR: It is found that albumin treatment reduced systemic inflammation and cardiocirculatory dysfunction in patients with decompensated cirrhosis and the immune-modulatory effects of albumin observed in the Pilot-PRECIOSA study were confirmed in the INFECIR-2 study.
149 citations
Authors
Showing all 2902 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Raghuram G. Rajan | 104 | 321 | 85900 |
| Paul Abrams | 91 | 505 | 51539 |
| Stanley W. Ashley | 83 | 498 | 29893 |
| Paula R Williamson | 82 | 516 | 29468 |
| Simon Travis | 78 | 421 | 29393 |
| David Lewis | 74 | 202 | 36038 |
| Beverley J. Hunt | 74 | 380 | 27474 |
| David Wright | 74 | 347 | 20178 |
| Nicholas J. Talbot | 71 | 240 | 29205 |
| Terry A. Howell | 62 | 310 | 14979 |
| Arvind H. Patel | 58 | 164 | 10724 |
| Fiona Lecky | 54 | 285 | 9999 |
| Jim G Thornton | 54 | 369 | 12237 |
| Sheena Reilly | 52 | 233 | 8061 |
| R. Jones | 51 | 515 | 12361 |