Institution
Guru Ghasidas University
Education•Bilaspur, Himachal Pradesh, India•
About: Guru Ghasidas University is a education organization based out in Bilaspur, Himachal Pradesh, India. It is known for research contribution in the topics: Catalysis & Drug delivery. The organization has 770 authors who have published 1482 publications receiving 19983 citations.
Topics: Catalysis, Drug delivery, Population, Raman spectroscopy, Dielectric
Papers published on a yearly basis
Papers
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TL;DR: The mechanism of action of the natural antioxidant compounds and assays and their reaction mechanisms can help in evaluating the antioxidant activity of various antioxidant compounds as well as in the development of novel antioxidants.
Abstract: The normal biochemical reactions in our body, increased exposure to the environment, and higher levels of dietary xenobiotic's result in the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS). The ROS and RNS create oxidative stress in different pathophysiological conditions. The reported chemical evidence suggests that dietary antioxidants help in disease prevention. The antioxidant compounds react in one-electron reactions with free radicals in vivo/in vitro and prevent oxidative damage. Therefore, it is very important to understand the reaction mechanism of antioxidants with the free radicals. This review elaborates the mechanism of action of the natural antioxidant compounds and assays for the evaluation of their antioxidant activities. The reaction mechanisms of the antioxidant assays are briefly discussed (165 references). Practical applications: understanding the reaction mechanisms can help in evaluating the antioxidant activity of various antioxidant compounds as well as in the development of novel antioxidants.
1,391 citations
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TL;DR: The applications of clustering in some fields like image segmentation, object and character recognition and data mining are highlighted and the approaches used in these methods are discussed with their respective states of art and applicability.
745 citations
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05 Sep 2013TL;DR: A number of biomass deconstruction or pretreatment processes have been used to break the structural framework of plants and depolymerize lignin, which is used for the production of biofuels and other value added products.
Abstract: The hunt for alternative sources of energy generation that are inexpensive, ecofriendly, renewable and can replace fossil fuels is on, owing to the increasing demands of energy. One approach in this direction is the conversion of plant residues into biofuels wherein lignocellulose, which forms the structural framework of plants consisting of cellulose, hemicellulose and lignin, is first broken down and hydrolyzed into simple fermentable sugars, which upon fermentation form biofuels such as ethanol. A major bottleneck is to disarray lignin which is present as a protective covering and makes cellulose and hemicellulose recalcitrant to enzymatic hydrolysis. A number of biomass deconstruction or pretreatment processes (physical, chemical and biological) have been used to break the structural framework of plants and depolymerize lignin. This review surveys and discusses some major pretreatment processes pertaining to the pretreatment of plant biomass, which are used for the production of biofuels and other value added products. The emphasis is given on processes that provide maximum amount of sugars, which are subsequently used for the production of biofuels.
409 citations
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TL;DR: This review focuses primarily on the Ras/Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways as therapeutic targets of anticancer drugs, their specific and dual inhibitors, structure activity relationships (SARs) and inhibitors under clinical trials.
400 citations
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TL;DR: A comprehensive study on molecular targets/pathways involved in carcinogenesis, mechanism of actions (MOAs), structure activity relationships (SARs) and patents granted have been highlighted and may be helpful for (medicinal) chemists to design more potent, safe, selective and cost effective anti-cancer chalcones.
363 citations
Authors
Showing all 799 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rakesh K. Chandra | 49 | 270 | 7483 |
Dilipkumar Pal | 40 | 158 | 5050 |
Anurag Srivastava | 39 | 431 | 6545 |
Ashok R. Patel | 39 | 122 | 4830 |
Anil Kumar Bajpai | 37 | 236 | 6005 |
Arijit Saha | 34 | 303 | 5470 |
Junji Inanaga | 34 | 126 | 4798 |
Anil Kumar | 34 | 335 | 8569 |
Alok Shukla | 32 | 260 | 5123 |
T.P. Sinha | 32 | 296 | 4892 |
Sunil Kumar Singh | 30 | 132 | 3733 |
Dhananjay Shukla | 29 | 122 | 2206 |
Ranjit T. Koodali | 27 | 92 | 3524 |
Kamlesh Shrivas | 26 | 98 | 2120 |
Subhash Banerjee | 26 | 115 | 2630 |