Institution
Hellenic Air Force
Government•Athens, Greece•
About: Hellenic Air Force is a government organization based out in Athens, Greece. It is known for research contribution in the topics: Denosumab & Osteoporosis. The organization has 304 authors who have published 434 publications receiving 8644 citations. The organization is also known as: Greek Air Force & HAF.
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TL;DR: It is shown that the STN is the best target to improve motor symptoms, postoperative cognitive deficit is mainly related to the surgery itself, and stimulation-induced hypomania is related to a combination of both the disease characteristics and a more ventral STN location.
Abstract: To further determine the causes of variable outcome from deep brain stimulation of the subthalamic nucleus (DBS-STN) in patients with Parkinson disease (PD). Data were obtained from our cohort of 309 patients with PD who underwent DBS-STN between 1996 and 2009. We examined the relationship between the 1-year motor, cognitive, and psychiatric outcomes and (1) preoperative PD clinical features, (2) MRI measures, (3) surgical procedure, and (4) locations of therapeutic contacts. Pre- and postoperative results were obtained in 262 patients with PD. The best motor outcome was obtained when stimulating contacts were located within the STN as compared with the zona incerta (64% vs 49% improvement). Eighteen percent of the patients presented a postoperative cognitive decline, which was found to be principally related to the surgical procedure. Other factors predictive of poor cognitive outcome were perioperative confusion and psychosis. Nineteen patients showed a stimulation-induced hypomania, which was related to both the form of the disease (younger age, shorter disease duration, higher levodopa responsiveness) and the ventral contact location. Postoperative depression was more frequent in patients already showing preoperative depressive and/or residual axial motor symptoms. In this homogeneous cohort of patients with PD, we showed that (1) the STN is the best target to improve motor symptoms, (2) postoperative cognitive deficit is mainly related to the surgery itself, and (3) stimulation-induced hypomania is related to a combination of both the disease characteristics and a more ventral STN location.
138 citations
TL;DR: Given the high incidence of PTMC as an incidental finding and the frequent multi-focality, doctors favor total or near-total thyroidectomy for the surgical management of nodular thyroid disease (multinodular goiter or dominant presumably benign thyroid nodule/s).
137 citations
TL;DR: FSW retainers bonded on the 6 mandibular anterior teeth might cause unexpected movements of anterior teeth to such an extent that retreatment is necessary, and clinicians should consider this possibility when planning the retention strategy.
127 citations
University of Padua1, Innsbruck Medical University2, University of Cambridge3, Charles University in Prague4, Michigan State University5, Ljubljana University Medical Centre6, AbbVie7, Lund University8, Drammen Hospital9, John Hunter Hospital10, Odense University Hospital11, AZ Groeninge12, Geneva College13, Aarhus University Hospital14, university of lille15, University of Liège16, Oslo University Hospital17, Autonomous University of Barcelona18, Université catholique de Louvain19, Palacký University, Olomouc20, University of Ulm21, Royal Adelaide Hospital22, University of Ioannina23, University of Tübingen24, Centre Hospitalier de Luxembourg25, Akershus University Hospital26, University of Toulouse27, Hellenic Air Force28, Stavanger University Hospital29, University of Copenhagen30, Carol Davila University of Medicine and Pharmacy31, Hannover Medical School32, University of Crete33, University of Rostock34, Haukeland University Hospital35, University Medical Center Groningen36, University of Turin37
TL;DR: LCIG treatment led to sustained improvements in motor fluctuations, non-motor symptoms particularly sleep/fatigue, mood/cognition and gastrointestinal domains, as well as quality of life in advanced PD patients over 24 months.
126 citations
TL;DR: The GRECCO-19 trial aims to identify whether colchicine may positively intervene in the clinical course of COVID-19 and results will be disseminated through peer-reviewed publications and conference presentations.
116 citations
Authors
Showing all 304 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Matthew G. Karlaftis | 43 | 202 | 8662 |
| George H. Sakorafas | 40 | 202 | 5493 |
| Kumares C. Sinha | 33 | 329 | 4741 |
| Athanasios Saratzis | 29 | 120 | 2829 |
| Polyzois Makras | 28 | 130 | 2651 |
| Athanasios Katsargyris | 27 | 133 | 2622 |
| Patrick S. McCarthy | 21 | 77 | 1506 |
| Athanasios Papatheodorou | 20 | 87 | 1577 |
| Maria P. Yavropoulou | 20 | 112 | 1648 |
| Nikolaos Melas | 19 | 45 | 995 |
| Efthimios D. Avgerinos | 19 | 82 | 1399 |
| Konstantina Delli | 18 | 60 | 950 |
| Dimitrios Kloukos | 18 | 46 | 785 |
| Hristos Tyralis | 17 | 60 | 1203 |
| P. Louka | 15 | 28 | 1266 |