Institution
Max Super Speciality Hospital
Healthcare•Delhi, India•
About: Max Super Speciality Hospital is a healthcare organization based out in Delhi, India. It is known for research contribution in the topics: Medicine & Cancer. The organization has 820 authors who have published 643 publications receiving 4193 citations.
Topics: Medicine, Cancer, Population, Internal medicine, Intensive care unit
Papers
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TL;DR: Important molecular characteristics have been identified that can subdivide this group of breast cancers further and can provide alternative systemic therapies and reliable predictive biomarkers and newer drugs against the known molecular pathways are required.
Abstract: Purpose
Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors comprising various breast cancers simply defined by the absence of estrogen receptor, progesterone receptor and overexpression of human epidermal growth factor receptor 2 gene In this review, we discuss the epidemiology, risk factors, clinical characteristics and prognostic variables of TNBC, and present the summary of recommended treatment strategies and all other available treatment options
419 citations
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TL;DR: All critical care survivors should be evaluated for PICS and those having signs and symptoms of it should be managed by a multidisciplinary team which includes critical care physician, neuro-psychiatrist, physiotherapist and respiratory therapist, with the use of pharmacological and non-apharmacological interventions.
Abstract: Survival of critically unwell patients has improved in the last decade due to advances in critical care medicine. Some of these survivors develop cognitive, psychiatric and /or physical disability after treatment in intensive care unit (ICU), which is now recognized as post intensive care syndrome (PICS). Given the limited awareness about PICS in the medical faculty this aspect is often overlooked which may lead to reduced quality of life and cause a lot of suffering of these patients and their families. Efforts should be directed towards preventing PICS by minimizing sedation and early mobilization during ICU.All critical care survivors should be evaluated for PICS and those having signs and symptoms of it should be managed by a multidisciplinary team which includes critical care physician, neuro-psychiatrist, physiotherapist and respiratory therapist, with the use of pharmacological and non-apharmacological interventions. This can be achieved through an organizational change and improvement, knowing the high rate of incidence of PICS and its adverse effects on the survivor's life and daily activities and its effect on the survivor's family.
378 citations
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University of Glasgow1, Brigham and Women's Hospital2, University Medical Center Groningen3, University of Minnesota4, Saarland University5, Max Super Speciality Hospital6, Fudan University7, Semmelweis University8, Montreal Heart Institute9, University of Toronto10, Yale University11, Copenhagen University Hospital12, The George Institute for Global Health13, University of Missouri–Kansas City14, National University of Cordoba15, Wrocław Medical University16, AstraZeneca17
TL;DR: Baseline kidney function did not modify the benefits of dapagliflozin on morbidity and mortality in HFrEF, and dapgliflozar slowed the rate of decline in eGFR, including in patients without diabetes.
Abstract: Background: Many patients with heart failure and reduced ejection fraction (HFrEF) have chronic kidney disease that complicates pharmacological management and is associated with worse outcomes. We ...
181 citations
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TL;DR: Future investigations in the management of sepsis should not only target good functional recovery but also ensure social independence and quality of life after ICU discharge.
Abstract: The incidence of severe sepsis and septic shock is increasing in the older population leading to increased admissions to the intensive care units (ICUs). The elderly are predisposed to sepsis due to co-existing co-morbidities, repeated and prolonged hospitalizations, reduced immunity, functional limitations and above all due to the effects of aging itself. A lower threshold and a higher index of suspicion is required to diagnose sepsis in this patient population because the initial clinical picture may be ambiguous, and aging increases the risk of a sudden deterioration in sepsis to severe sepsis and septic shock. Management is largely based on standard international guidelines with a few modifications. Age itself is an independent risk factor for death in patients with severe sepsis, however, many patients respond well to timely and appropriate interventions. The treatment should not be limited or deferred in elderly patients with severe sepsis only on the grounds of physician prejudice, but patient and family preferences should also be taken into account as the outcomes are not dismal. Future investigations in the management of sepsis should not only target good functional recovery but also ensure social independence and quality of life after ICU discharge.
176 citations
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TL;DR: Bariatric surgery should be considered for the treatment of obesity for acceptable Asian candidates with BMI with or without co-morbidities and new surgical indication for Asian patients should be discussed by the expert of this field.
Abstract: Associations of BMI with body composition and health outcomes may differ between Asian and European populations. Asian populations have also been shown to have an elevated risk of type 2 diabetes, hypertension, and hyperlipidemia at a relatively low level of BMI. New surgical indication for Asian patients should be discussed by the expert of this field. Forty-four bariatric experts in Asia-Pacific and other regions were chosen to have a voting privilege for IFSO-APC Consensus at the 2nd IFSO-APC Congress. A computerized audience-response voting system was used to analyze the agreement with the sentence of the consensus. Of all delegates, 95% agreed with the necessity of the establishment of IFSO-APC consensus statements, and 98% agreed with the necessity of a new indication for Asian patients.
134 citations
Authors
Showing all 835 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bharat B. Aggarwal | 175 | 706 | 116213 |
Vinay Sakhuja | 42 | 275 | 6119 |
Om Prakash | 39 | 294 | 6511 |
Akhilesh Kumar Singh | 37 | 280 | 4628 |
Pradeep Chowbey | 29 | 118 | 4176 |
Kewal K. Talwar | 29 | 173 | 3502 |
Pramod Kumar Julka | 25 | 203 | 2933 |
Anil Sharma | 24 | 96 | 1840 |
Manish Baijal | 24 | 80 | 1760 |
Rajesh Khullar | 24 | 89 | 1792 |
Ramandeep Singh Arora | 22 | 83 | 1943 |
Vandana Soni | 22 | 73 | 1384 |
Deven Juneja | 17 | 65 | 959 |
Rahul Naithani | 17 | 106 | 882 |
Premashish Kar | 16 | 61 | 985 |