Archives of Gynecology and Obstetrics 

About: Archives of Gynecology and Obstetrics is an academic journal published by Springer Science+Business Media. The journal publishes majorly in the area(s): Pregnancy & Medicine. It has an ISSN identifier of 0932-0067. Over the lifetime, 17380 publications have been published receiving 174589 citations. The journal is also known as: Gynecology and obstetrics.

The principle of hope

Abstract: Der unheilbare Kranke, der zu uns in die Klinik kommt, erwartet von uns Trost. Wie aber k6nnen wir einem unheilbar Kraken einen wahren Trost geben, wenn er doch weig, dab sein Leben durch seine Krankheit begrenzt ist? Eine Antwort darauf w/ire zun/ichst eine Forderung: Wer tr6sten will, mug mitffhlen und mitempfinden k6nnen, ja mug auch mitleiden k6nnen. Wer also einen Kranken tr6sten will, mug den anderen in seinem Leid ernst nehmen und darf nichts bagatellisieren. In unseren Seminaren zur Begleitung von Krebskranken und deren Angeh6rigen bitten wir die Teilnehmer, zum Thema: ,,Wie erlebe ich Krankheit" etwas in Farbe zu malen. Es ist erschreckend, wie negativ gerade Medizinstudenten sich hierbei ausdrficken. Krankheit scheint ffr sie eine niederdrfickende Erfahrung zu sein. Der Kranke wird eingeschlossen und kann sich nicht mehr wehren. So die Krankheit erfahren, kann mich nicht mitempfinden lassen, was im Kranken abl/iuft und verhindert, wahren Trost zu spenden, denn Trost, einem Patienten und seinen Angeh6rigen gegeben, ist auf Hoffnung bezogen. Tr6sten kann nur, wer Hoffnung hat und den Grund der Hoffnung kennt. Wenn ich davon ausgehe, dab filir mich Gott Inbegriff und Ziel der Hoffnung ist, dann ist der Gott der Hoffnung deshalb auch immer der Gott des Trostes. Vielleicht kommen wir heute beim Wort Trost und Hoffnung in Verlegenheit, weil wir bei unserem Trost den Trost Gottes vergessen und weil unsere eigene Hoffnung nicht grog und lebendig genug ist. Sicher dfirfen wir es uns nicht allzu einfach machen und glauben, Worte vom Trost Gottes k6nnen als Patentrezepte dienen. Es gentigt auch nicht, einfach Gott, Jesus Christus, Kreuz und Auferstehung nebeneinander zu stellen und in Anspruch zu nehmen, um den Patienten auf irgendeine fibernatfirliche Kraft zu verweisen. Das w/ire ein VertrSsten und unbarmherzig gegenfiber dem Patienten und seinen Angeh6rigen. Vielleicht lehren uns unsere Patienten am besten, wenn wir genau zuh6ren, was ihnen hilft, Hoffnung in der Krankheit zu behalten. In den Bildern, die unsere Patienten malen, kommt diese Hoffnung, dieser Trost, den sie empfangen haben, immer wieder zum Ausdruck. Die Diagnose Krebs ist f f r viele Patienten gleichsam ein furchtbares schwarzes Tier, das den ganzen Menschen zu ergreifen droht. Aber dann kommen Menschen, die den Kranken Hoffnung geben, die ihm zeigen, dab er nicht alleine den Kampf gegen die Krankheit f~hren mug. Es kommen Arzte, die den Kranken mit allen seinen Angsten und N6ten ernst nehmen, die ihm verdeutlichen, dab er die Krankheit nicht als Todesurteil erleben mug, dab er vielmehr hoffen darf, selbst bei einer unheilbaren Krankheit, das ihm verbliebene Leben als noch wertvoll erleben zu k6nnen.

An Overview of Triple-Negative Breast Cancer

Abstract: Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors comprising various breast cancers simply defined by the absence of estrogen receptor, progesterone receptor and overexpression of human epidermal growth factor receptor 2 gene In this review, we discuss the epidemiology, risk factors, clinical characteristics and prognostic variables of TNBC, and present the summary of recommended treatment strategies and all other available treatment options

Fetal growth restriction: current knowledge.

Abstract: Fetal growth restriction (FGR) is a condition that affects 5–10% of pregnancies and is the second most common cause of perinatal mortality. This review presents the most recent knowledge on FGR and focuses on the etiology, classification, prediction, diagnosis, and management of the condition, as well as on its neurological complications. The Pubmed, SCOPUS, and Embase databases were searched using the term “fetal growth restriction”. Fetal growth restriction (FGR) may be classified as early or late depending on the time of diagnosis. Early FGR (<32 weeks) is associated with substantial alterations in placental implantation with elevated hypoxia, which requires cardiovascular adaptation. Perinatal morbidity and mortality rates are high. Late FGR (≥32 weeks) presents with slight deficiencies in placentation, which leads to mild hypoxia and requires little cardiovascular adaptation. Perinatal morbidity and mortality rates are lower. The diagnosis of FGR may be clinical; however, an arterial and venous Doppler ultrasound examination is essential for diagnosis and follow-up. There are currently no treatments to control FGR; the time at which pregnancy is interrupted is of vital importance for protecting both the mother and fetus. Early diagnosis of FGR is very important, because it enables the identification of the etiology of the condition and adequate monitoring of the fetal status, thereby minimizing risks of premature birth and intrauterine hypoxia.

The pathophysiology of endometriosis and adenomyosis: tissue injury and repair

Abstract: Introduction This study presents a unifying concept of the pathophysiology of endometriosis and adenomyosis. In particular, a physiological model is proposed that provides a comprehensive explanation of the local production of estrogen at the level of ectopic endometrial lesions and the endometrium of women affected with the disease.

Pregnancy outcome at age 40 and older.

Abstract: Objective: Our purpose was to examine pregnancy outcomes among women age 40 or older. Methods: Between January, 1997 and December 1999, we performed a case-control study compared pregnancy outcomes of 468 patients delivered at our hospital at > Or = 40 years old with outcomes in a control group consisting of the next two deliveries of women with ages 20 to 29 years. Retrospective analysis of the antepartum and intrapartum records was done to compare clinical outcome. Results: Approximately 25,356 women delivered during the study period, and 468 (1.8%). Of these women were at age 40 or older. Of this latter group, 50 (10.7%) were nulliparous. Mean birthweight of infants delivered by older nulliparous women was significantly lower than that among nulliparous controls (3210 ± 5 vs. 3320 ± 1 g), whereas mean birth weight in the group of older multiparous was not different than that among younger multiparous controls (3370 ± 1 vs. 3365 ± 4 g). Gestational age at delivery was significantly lower among older nulliparous, and multiparous compared with nulliparous and multiparous younger controls. Older women were at increased risk for cesarean delivery (nulliparous 18%; multiparous 14%) compared with nulliparous and multiparous younger control groups (nulliparous 8%; multiparous 6%). In the study group, the operative vaginal delivery rate was higher than that of the control group. The study groups were more likely to develop gestational diabetes, preeclampsia, and placenta praevia. Older nulliparous had an increased incidence of malpresentation, abnormal labour patterns, special care baby unit admission (SCBU), and low 1-minute Apgar score. Older multiparous were more likely to experience birth asphyxia, premature rupture of membranes, and antepartum vaginal bleeding. Conclusion: Nulliparous women age 40 or over have a higher risk of operative delivery than do youngr nulliparous women. This increase occurs in spite of lower birth weight and gestational age and may be explained by the increase incidence of obstetric complications. Although maternal morbidity was increased in the older women, the overall neonatal outcome did not appear to be affected.