Muş Alparslan University

About: Muş Alparslan University is a education organization based out in Muş, Turkey. It is known for research contribution in the topics: Band gap & Magnetic field. The organization has 259 authors who have published 808 publications receiving 7210 citations.

Mutagenic and antimutagenic properties of some lichen species grown in the Eastern Anatolia Region of Turkey

Abstract: All the methanol extracts did not show mutagenic activity in Ames/Salmonella and Z. mays MI test systems. Furthermore, some extracts showed significant antimutagenic activity against 9-AA in Ames test system. Inhibition rates for 9-AA mutagenicity ranged from 25.51% (P. furfuracea - 0.05 microg/plate) to 66.14% (C. islandica - 0.05 microg/plate). In addition, all of the extracts showed significant antimutagenic activity against sodium azide (NaN3) mutagenicity on MI values of Z. mays.

Unravelling the phenolic compound reserves, antioxidant and enzyme inhibitory activities of an endemic plant species, Achillea pseudoaleppica.

Abstract: The present ethnobotanical study unravelled the phenolic reservoir (UHPLC-MS/TQ-MS) and pharmacological activity (antioxidant and enzyme inhibitory activities) of an endemic plant, Achillea pseudoaleppica Hub.-Mor. (Asteraceae). The effective antioxidant properties of ethanol and water extracts of A. pseudoaleppica leaves were determined by using six different in vitro bioanalytical methods including three reducing antioxidant methods and three radical scavenging antioxidant methods. In the other step of the study, the enzyme inhibitory effects of water and ethanol extracts of A. pseudoaleppica were determined against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, and α-glucosidase enzymes. The ethanol extract was found to have effective inhibition potential for all four respected enzymes. The IC50 values of A. pseudoaleppica extract against AChE, BChE, α-amylase, and α-glucosidase enzymes were found to be 2.67 mg/mL, 4.55 mg/mL, 16.51 mg/mL, and 12.37 mg/mL, respectively. Also, UHPLC-MS/TQ-MS analyses revealed quinic acid as the most abundant phenolic compound of the water extract (31.12 ± 1.65 µg/mg) and ethanol extract (11.75 ± 0.82 µg/mg). In addition, the molecular docking interaction of the most abundant phenolic compound of A. pseudoaleppica (quinic acid) with AChE, BChE, α-amylase, and α-glucosidase target enzymes were evaluated using Chimera and AutoDock Vina softwares. In conclusion, the rich phenolic content and the potent antioxidant and enzyme inhibitory properties of A. pseudoaleppica extracts may support the widespread ethnobotanical use of the plant application.Communicated by Ramaswamy H. Sarma.

Thermal degradation of two different polymers bearing amide pendant groups prepared by ATRP method

Abstract: Piperidinocarbonylmethyl methacrylate (PyCMMA) and 1-(piperidinocarbonyl) ethylmethacrylate (PyCEMA) monomers were synthesized. Polymerizations of PyCMMA and PyCEMA were carried out by atom transfer radical polymerization. The structure of monomers and polymers was characterized by 1H-NMR, 13C-NMR, and FT-IR spectroscopies. Characterization of poly(PyCMMA) and poly(PyCEMA) were carried out using differential scanning calorimetry and gel permeation chromatography. The experimental results showed that the reaction exhibited characteristics of controlled polymerization. The thermal degradation behaviors of poly(PyCEMA) and poly(PyCMMA) were studied using thermogravimetry and a single line vacuum system consisting of a degradation tube with a condenser for product collection. The poly(PyCEMA) and poly(PyCMMA) were heated from ambient temperature to 325 and 500 °C, respectively. The products of degradation were collected as a cold ring fraction (CRF). The CRFs of degradation were investigated by means of IR, 1HNMR, and GC-MS. For the degradation of both polymers, the major products of CRFs are piperidinocarbonyl methanol and 1,2-dipiperidino,1-oxo ethane. The GC-MS, IR, and NMR data showed that depolymerization below 325 °C to the corresponding monomer was not prominantin the thermal degradation of poly(PyCMMA). The mode of thermal degradation including formation of the major products was identified.

$$\varphi $$ φ -Best proximity point theorems and applications to variational inequality problems

Abstract: The main concern of this study is to introduce the notion of $$\varphi $$ -best proximity points and establish the existence and uniqueness of $$\varphi $$ -best proximity point for non-self mappings satisfying $$(F,\varphi )$$ -proximal and $$(F,\varphi )$$ -weak proximal contraction conditions in the context of complete metric spaces. Some examples are supplied to support the usability of our results. As applications of the obtained results, some new best proximity point results in partial metric spaces are presented. Furthermore, sufficient conditions to ensure the existence of a unique solution for a variational inequality problem are also discussed.

A new method for inextensible flows of timelike curves in 4-dimensional LP-Sasakian manifolds

Abstract: Inextensible flows of timelike curves plays an important role in practical applications. In this paper, we construct a new method for inextensible flows of timelike curves in a conformally flat, quasi conformally flat and conformally symmetric 4-dimensional LP-Sasakian manifold. With this new representation, we derive the necessary and sufficient condition for the given curve to be the inextensible flow. By using curvature tensor field, we give some characterizations for curvatures of a timelike curve in a conformally flat, quasi conformally flat and conformally symmetric 4-dimensional LP-Sasakian manifold. Finally, we obtain flows of some associated curves of timelike curves.