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Institution

Novus International

About: Novus International is a based out in . It is known for research contribution in the topics: Methionine & Feed conversion ratio. The organization has 269 authors who have published 256 publications receiving 7557 citations. The organization is also known as: Novus International, Inc..


Papers
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Journal ArticleDOI
TL;DR: The biological basis for antibiotic effects on animal growth efficiency will consider effects on intestinal microbiota and effects on the host animal and will use the germ-free animal to illustrate effects of the conventional microflora.

1,239 citations

Journal ArticleDOI
TL;DR: Organic acids have several additional effects that go beyond those of antibiotics, including reduction in digesta pH, increased pancreatic secretion, and trophic effects on the gastrointestinal mucosa, much more is known about these effects in swine than in poultry.
Abstract: Approvals for the use of nontherapeutic antibiotics in animal feed are fast disappearing worldwide. The primary effect of antibiotics is antimicrobial; all of the digestibility and performance effects can by explained by their impact on the gastrointestinal microflora. Among the candidate replacements for antibiotics are organic acids, both individual acids and blends of several acids. Like antibiotics, short-chain organic acids also have a specific antimicrobial activity. Unlike antibiotics, the antimicrobial activity of organic acids is pH dependent. Organic acids have a clear and significant benefit in weanling piglets and have been observed to benefit poultry performance. Organic acids have antimicrobial activity; however, there appear to be effects of organic acids beyond those attributed to antimicrobial activity. Reductions in bacteria are associated with feeding organic acids, which are particularly effective against acid-intolerant species such as E. coli, Salmonella and Campylobacter. Both antibiotics and organic acids improve protein and energy digestibilities by reducing microbial competition with the host for nutrients and endogenous nitrogen losses, by lowering the incidence of subclinical infections and secretion of immune mediators, and by reducing production of ammonia and other growth-depressing microbial metabolites. Organic acids have several additional effects that go beyond those of antibiotics. These include reduction in digesta pH, increased pancreatic secretion, and trophic effects on the gastrointestinal mucosa. Much more is known about these effects in swine than in poultry. There appears to be more variability in detecting an organic acid benefit in comparison to that observed with antibiotics. Lack of consistency in demonstrating an organic acid benefit is related to uncontrolled variables such as buffering capacity of dietary ingredients, presence of other antimicrobial compounds, cleanliness of the production environment, and heterogeneity of gut microbiota. Additional research can clarify the role of these factors and how to minimize their impact.

533 citations

Journal ArticleDOI
TL;DR: These results showed considerable variation in lameness and leg injury prevalence as well as facility design and management among freestall farms in North America, suggesting great opportunities for improvement on other farms within the region.

256 citations

Journal ArticleDOI
TL;DR: These studies support detailed compositional analysis of the GTS seeds, which showed no meaningful differences between the parental and GTS lines in the concentrations of important nutrients and antinutrients.
Abstract: Animal feeding studies were conducted with rats, broiler chickens, catfish and dairy cows as part of a safety assessment program for a soybean variety genetically modified to tolerate in-season application of glyphosate. These studies were designed to compare the feeding value (wholesomeness) of two lines of glyphosate-tolerant soybeans (GTS) to the feeding value of the parental cultivar from which they were derived. Processed GTS meal was incorporated into the diets at the same concentrations as used commercially; diary cows were fed 10 g/100 g cracked soybeans in the diet, a level that is on the high end of what is normally fed commercially. In a separate study, laboratory rats were fed 5 and 10 g unprocessed soybean meal 100 g diet. The study durations were 4 wk (rats and dairy cows), 6 wk (broilers) and 10 wk (catfish). Growth, feed conversion (rats, catfish, broilers), fillet composition (catfish), and breast muscle and fat pad weights (broilers) were compared for animals fed the parental and GTS lines. Milk production, milk composition, rumen fermentation and nitrogen digestibility were also compared for dairy cows. In all studies, measured variables were similar for animals fed both GTS lines and the parental line, indicating that the feeding value of the two GTS lines is comparable to that of the parental line. These studies support detailed compositional analysis of the GTS seeds, which showed no meaningful differences between the parental and GTS lines in the concentrations of important nutrients and antinutrients. They also confirmed the results of other studies that demonstrated the safety of the introduced protein, a bacterial 5-enolpyruvyl-shikimate-3-phosphate synthase from Agrobacterium sp. strain CP4.

214 citations

Patent
18 Feb 1997
TL;DR: In this article, a fleet of vehicles to provide material to a plurality of tanks at various customer locations is used to minimize total delivered cost for the products based on the projected future tank levels and the possible routes to dispatch each of the vehicles.
Abstract: The system and method include a fleet of vehicles to provide material to a plurality of tanks at various customer locations. An inventory indicator associated with each of the tanks provides a quantity signal to the central station indicating the quantity and temperature of each of the tanks. A processor at the central staiion monitors the quantity signals of each of the tanks to determine past usage rates of the contents of each of the tanks. The processor projects future tank quantities based on the past usage pattern and determines possible routes for each of the vehicles to each of the tanks. The processor optimizes the routes, delivery amounts, and delivery schedule to minimize total delivered cost for the products based on the projected future tank levels and the possible routes to dispatch each of the vehicles.

191 citations


Authors

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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20219
202016
20193
201810
201716
201614